Abstract
THE small intestine is particularly susceptible to damage by ionizing radiation, and both morphological and functional studies have demonstrated a wide range of changes1–5. Histological changes can be observed 3 h after exposure and with moderate dose irradiation usually reach a maximum within three to four days, rapidly returning to a normal picture five days after irradiation. Functional changes parallel this time sequence, and motility, absorption availability, absorption and protein leakage have all been studied. Some doubt has recently been cast on the significance of polyvinyl pyrrolidone (PVP) excretion as an absolute measure of protein leak age6, and it was felt desirable to study the problem further using albumin labelled with iodine-131.
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BROMFIELD, A., DYKES, P. Radiation-induced Protein Leakage into the Small Intestine. Nature 201, 633–634 (1964). https://doi.org/10.1038/201633a0
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DOI: https://doi.org/10.1038/201633a0
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