Abstract
REACTIONS to parenteral administration of endotoxin in mammals include pyrexia, leukopænia followed by leukocytosis, vasodilation, and irreversible shock1. Spink2 reviewed the actions of snake venom and endotoxin, and concluded that their mechanism of action is similar; however, in recent studies Condie et al.3 showed that there are few parallels between the biological responses of rabbits to Escherichia coli endotoxin and Agkistrodon piscivorus venom and that the two toxins are distinct immunochemically.
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References
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PAPERMASTER, B., CONDIE, R., GOOD, R. et al. Toxicity of Endotoxin and Snake Venom in the Hagfish. Nature 195, 84 (1962). https://doi.org/10.1038/195084a0
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DOI: https://doi.org/10.1038/195084a0
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