Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Evidence for the Existence of Two Corticotrophin-releasing Factors, α and β

Nature volume 188, pages 1192–1193 (1960)Cite this article

Abstract

WE wish to report here the presence of two distinct peptides with corticotrophin-releasing factor activity in hog posterior pituitary extracts. All the separation methods as well as the bioassays for corticotrophin-releasing factor, adrenocorticotrophic hormone, vasopressin and melanocyte stimulating hormone have been described previously1–6.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Guillemin, R., Hearn, W. H., Cheek, W. R., and Housholder, D. E., Endocrinol., 60, 488 (1957).

    Article  CAS  Google Scholar 

  2. Schally, A. V., Saffran, M., and Zimmerman, B., Biochem. J., 70, 97 (1958).

    Article  CAS  Google Scholar 

  3. Schally, A. V., and Guillemin, R., Tex. Rep. Biol. Med., 18, 133 (1960).

    CAS  PubMed  Google Scholar 

  4. Guillemin, R., and Schally, A. V., Endocrinol., 65, 555 (1959).

    Article  CAS  Google Scholar 

  5. Schally, A. V., Andersen, R. N., Long, J. M., and Guillemin, R., Proc. Soc. Exp. Biol. Med., 104, 290 (1960).

    Article  CAS  Google Scholar 

  6. Schally, A. V., and Guillemin, R., Proc. Soc. Exp. Biol. Med., 100, 138 (1959).

    Article  CAS  Google Scholar 

  7. Harris, J. I., Biochem. J., 71, 451 (1959).

    Article  CAS  Google Scholar 

  8. Gros, C., and Privat de Garilhe, M., C.R. Acad. Sci., Paris, 249, 2234 (1959).

    CAS  Google Scholar 

  9. Royce, P. C., and Sayers, G., Proc. Soc. Exp. Biol. Med., 103, 447 (1960).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, Baylor University College of Medicine, Houston, Texas

    A. V. SCHALLY, R. N. ANDERSEN, H. S. LIPSCOMB, J. M. LONG & ROGER GUILLEMIN

  2. Laboratoire de Morphologie expérimentale et Endocrinologie, College de France, Paris

    A. V. SCHALLY, R. N. ANDERSEN, H. S. LIPSCOMB, J. M. LONG & ROGER GUILLEMIN

Authors
  1. A. V. SCHALLY
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. N. ANDERSEN
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. S. LIPSCOMB
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. M. LONG
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. ROGER GUILLEMIN
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SCHALLY, A., ANDERSEN, R., LIPSCOMB, H. et al. Evidence for the Existence of Two Corticotrophin-releasing Factors, α and β. Nature 188, 1192–1193 (1960). https://doi.org/10.1038/1881192a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1881192a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing