Abstract
ESTIMATES of the MNSs gene frequencies in the English population have been based hitherto on the results of tests with anti-M, -N and -S only1,2. Recently, a supply of the very rare anti-s was made available through the kindness of Dr. J. O'Riordan of Dublin3, and a random series of 1,000 Sutton blood donors was tested with all four antisera. The samples were also tested with anti-Mia, -Vw and -Mg. All were negative with the last two antisera, but one donor was found to be Ms/Ns, Mi(a +) Vw −, and a study of her family showed Mi a to be travelling with Ns. The results of the major grouping tests are given in Table 1.
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References
Race, R. R., and Sanger, R., “Blood Groups in Man”, 51 (1950); 62 (1954); 74 (1958) (Oxford University Press).
Ikin, E. W., et al., cited by Mourant, A. E., in “The Distribution of the Human Blood Groups”, 358 (Oxford University Press, 1954).
O'Riordan, J., and Cann, J., Vox Sang., (N.S.), 4, 242 (1959).
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CLEGHORN, T. MNSs Gene Frequencies in English Blood Donors. Nature 187, 701 (1960). https://doi.org/10.1038/187701a0
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DOI: https://doi.org/10.1038/187701a0
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