Abstract
A PRELIMINARY report by Katznelson and Jamieson1 on the effect of the antibiotic fumagillin (derived from an Aspergillus culture designated H–32) upon the infection of the adult honey bee by the microsporidian Nosema apis indicated promising results. They suggested that the action of the drug was prophylactic in nature, killing the infective amœboid, phase which is released from the spore into the ventricular lumen prior to its entry into the epithelial cells. This view was probably suggested by the results of McCowen et al.3, which showed a depressant action of the drug upon the growth of bacteria-free cultures of Endamœba hystolytica.
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References
Katznelson, H., and Jamieson, C. A., Science, 115, 70 (1952).
Hanson, F. R., and Eble, E. J., J. Bact., 58, 527 (1949).
McCowen, M. C., Callender, M. E., and Lawlis, J. F., Science, 113, 202 (1951).
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BAILEY, L. Effect of Fumagillin upon Nosema apis (Zander). Nature 171, 212–213 (1953). https://doi.org/10.1038/171212a0
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DOI: https://doi.org/10.1038/171212a0
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