Abstract
The intermembrane space of mitochondria is home to several potentially lethal proteins, including pro-apoptotic caspases. The observation that caspase-9 moves from mitochondria into the nucleus on the induction of apoptosis provides this caspase with a possible new role.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Li, P. et al. Cell 91, 479–489 (1997).
Susin, S. A. et al. J. Exp. Med. 189, 381– 394 (1999).
Susin, S. A. et al. Nature 397, 441–446 (1999).
Krajewski, S. et al. Proc. Natl Acad. Sci. USA 96, 5752– 5757 (1999).
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T. & Alnemri, E. S. Mol. Cell 1, 949–957 ( 1998).
Kuida, K. et al. Cell 94, 325–337 (1998).
Hakem, R. et al. Cell 94, 339–352 (1998).
Luo, X., Budihardjo, I., Zou, H., Slaughter, C. & Wang, X. Cell 94, 481– 490 (1998).
Li, H., Zhu, H., Xu, C.-J. & Yuan, J. Cell 94, 491–501 (1998).
Cecconi, F., Alvarez-Bolado, G., Meyer, B. I., Roth, K. A. & Gruss, P. Cell 94, 727 –737 (1998).
Yoshida, H. et al. Cell 94, 739–750 (1998).
Soengas, M. S. et al. Science 284, 156–159 (1999).
Saleh, A., Srinivasula, S. M., Acharya, S., Fishel, R. & Alnemri, E. J. Biol. Chem.he press).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Alnemri, E. Hidden powers of the mitochondria. Nat Cell Biol 1, E40–E42 (1999). https://doi.org/10.1038/10034
Issue Date:
DOI: https://doi.org/10.1038/10034