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MicroRNAs as potential cancer therapeutics

Oncogene volume 27, pages S52–S57 (2008)Cite this article

Abstract

MicroRNAs (miRNAs) have been shown to have an important role in various cellular processes, such as apoptosis, differentiation and development. Recent studies have shown that miRNAs are mis-expressed in human cancers where they can exert their effect as oncogenes or tumor suppressors. Here, we review the potential for using miRNAs as biomarkers for diagnosis, prognosis and cancer therapies.

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Authors and Affiliations

  1. Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, USA

    P Trang & F J Slack

  2. Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA

    P Trang & J B Weidhaas

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  1. P Trang
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Correspondence to F J Slack.

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Trang, P., Weidhaas, J. & Slack, F. MicroRNAs as potential cancer therapeutics. Oncogene 27 (Suppl 2), S52–S57 (2008). https://doi.org/10.1038/onc.2009.353

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