Abstract
The macrophage scavenger receptor 1 gene (MSR1) was recently identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. To confirm these findings, we screened MSR1 for germline mutations among individuals with familial prostate cancer and tested gene variants for associations in both sporadic and familial prostate cancer. Our results do not support MSR1 as a risk factor for prostate cancer.
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Acknowledgements
We thank D. Johnson for secretarial support. This study was supported by grants from the Public Health Service, US National Institutes of Health.
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Wang, L., McDonnell, S., Cunningham, J. et al. No association of germline alteration of MSR1 with prostate cancer risk. Nat Genet 35, 128–129 (2003). https://doi.org/10.1038/ng1239
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DOI: https://doi.org/10.1038/ng1239
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