Abstract
Octreotide (Sandostatin 201-995) has aninhibitory effect on gastric, intestinal, and pancreaticsecretions and hepatic and splachnic blood flow. Weexamined the effects of octreotide on bile flow and bile components in 10 patients with T-tubecholedochostomy. A Fogarty balloon catheter was inserteddistal to the T-tube of these patients for measurementof bile flow and bile components. Bile samples were obtained to analyze bile acid, phospholipid,lipoprotein, and cholesterol, and bile flow measurementswere performed every 15 min for a period of 90 minbefore study and after normal saline and octreotide administrations. While octreotide had aninhibitory effect on bile flow, the concentrations ofbile acid, phospholipid, and lipoprotein in bile wereincreased with octreotide.
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Sahin, M., Kartal, A., Belviranli, M. et al. Effect of Octreotide (Sandostatin 201-995) on Bile Flow and Bile Components. Dig Dis Sci 44, 181–185 (1999). https://doi.org/10.1023/A:1026630923206
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DOI: https://doi.org/10.1023/A:1026630923206