Abstract
A facile synthetic approach to 2,5-diketopiperazines 4 by the Ugi four-center three-component reaction using commercially available dipeptides as a bifunctional component, aldehydes, and isocyanides was described.
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Cho, S., Keum, G., Kang, S.B. et al. An efficient synthesis of 2,5-diketopiperazine derivatives by the Ugi four-center three-component reaction. Mol Divers 6, 283–286 (2003). https://doi.org/10.1023/B:MODI.0000006812.16141.b5
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DOI: https://doi.org/10.1023/B:MODI.0000006812.16141.b5