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Prevalence of HCV infection among health care workers in a hospital in central Italy

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Abstract

Health care workers are at risk of acquiring transmissible diseases. Controversial results have been reported about HCV. The aims of the present study are to assess the prevalence of HCV in health care workers in Pistoia General Hospital (central Italy) and to compare prevalence with other groups, particularly with a sample of the general population. Serum samples collected from 511 health care employees engaged in direct clinical task and 222 clerical and nurse school attendees have been tested by ELISA and confirmed by RIBA. Total seroprevalence was 3.8%: 4.7% in the first group; 1.8% in the second group. The data showed a slight increase in prevalence by age and not by length of stay in the health care workers' group. Comparison of HCV prevalence with blood donors from the province of Pistoia and the general population from Sersale (Catanzaro, southern Italy), restricted to under-40 subjects, indicates an increasing trend in this order: Blood donors, general population, clerical and nursing school attendees, health care workers' group with the highest value (3.4%). A cohort study is needed to evaluate pattern of HCV seroconversion.

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References

  1. Seef LB. Natural history of hepatitis C. Hepatology 1997; 26(Suppl 1): 21s-28s.

    Google Scholar 

  2. Alter MJ, Hadler SC, Judson FN, et al. Risk factors for acute non-A non-B hepatitis in the United States and association with hepatitis C virus infection. JAMA 1990; 264: 2231-2235.

    Google Scholar 

  3. Sartori M, La Terra G, Aglietta M, Manzin A, Navino C, Verzetti G. Transmission of Hepatitis C virus via blood splash into conjunctiva [Letter]. Scand J Infect Dis 1993; 25: 270-271.

    Google Scholar 

  4. De Luca M, Ascione A, Vacca C, Zarone A. Are health-care workers really at risk of HCV infection? [Letter]. Lancet 1992; 339: 1364-1365.

    Google Scholar 

  5. Herbert AM, Walker DM, Davies KJ, Bagg J. Occupationally acquired hepatitis C virus infection [Letter]. Lancet 1992; 339: 305.

    Google Scholar 

  6. Alter MJ. Occupational exposure to hepatitis C virus: A dilemma [Editorial]. Infect Control Hosp Epidemiol 1994; 15: 742-744.

    Google Scholar 

  7. Lanphear BP, Linnemann CC Jr, Cannon CG, De-Ronde MM, Pendy L, Kerley LM. Hepatitis C virus infection in healthcare workers: Risk of exposure and infection. Infect Control Hosp Epidemiol 1994; 15: 745-750.

    Google Scholar 

  8. Alter MJ. The detection, transmission and outcome of hepatitis C virus infection. Infect Ag Dis 1993; 2: 155-166.

    Google Scholar 

  9. Puro V, Petrosillo N, Ippolito G, Jagger J. Hepatitis C virus infection in healthcare workers [Letter]. Infect Control Hosp Epidemiol 1995; 16: 324-325.

    Google Scholar 

  10. Cariani E, Zonaro A, Primi D, et al. Detection of hepatitis C virus RNA and antibodies after needlestick. Lancet 1991; 337: 850.

    Google Scholar 

  11. Kiyosawa K, Sodeyaama T, Tanaka E, et al. Hepatitis C in hospital employees with needlestick injuries. Ann Intern Med 1991; 115: 367-369.

    Google Scholar 

  12. Mitsui T, Iwano K, Masuko K, et al. Hepatitis C virus infection in medical personnel after needlestick accident. Hepatology 1992; 16: 1109-1114.

    Google Scholar 

  13. Gerberding JL. Incidence and prevalence of human immunodeficiency virus, hepatitis B virus and cytomegalovirus among health care personnel at risk for blood exposure: Final report from a longitudinal study. J Infect Dis 1994; 170: 1410-1417.

    Google Scholar 

  14. Khuri-Bulos NA, Toukan A, Mahafzah A, et al. Epidemiology of needlestick and sharp injuries at a university hospital in a developing country: A 3-years prospective study at the Jordan University Hospital, 1993 through 1995. Am J Infect Control 1997; 25: 322-329.

    Google Scholar 

  15. Guadagnino V, Stroffolini T, Rapicetta M, et al. Prevalence, risk factors, and genotype distribution of hepatitis C virus infection in the general Population: A community-based survey in southern Italy. Hepatology 1997; 26: 1006-1011.

    Google Scholar 

  16. Maggi G, Armitano S, Brambilla L, et al. Hepatitis C infection in an Italian population not selected for risk factors. Liver 1999; 19: 427-431.

    Google Scholar 

  17. Metha CR, Patel NR. StaXact4. Cambridge, Massachusetts, USA: CYTEL Software Corporation, 1999.

    Google Scholar 

  18. Centers for Disease Control and Prevention-World Health Organization. EPI-INFO 6, Atlanta, Georgia, USA, Geneva, CH, 1996.

  19. Stata Corporation. Stata 6, 702 University Drive East, College Station, TX 77840, USA, 1999.

  20. Klein R, Freeman K, Taylor PE, Stevens CE. Occupational risk factors for hepatitis C virus infection among New York City dentists. Lancet 1991; 338: 1539-1542.

    Google Scholar 

  21. Herbert AM, Walker DM, Davies KJ, Bagg J. Occupationally acquired hepatitis C virus infection. Lancet 1992; 339: 304-305.

    Google Scholar 

  22. Thomas DL, Gruninger SE, Siew C, Joy ED, Quinn TC. Occupational risk of hepatitis C infections among dentists and oral surgeons in North America. Am J Med 1996; 100: 41-45.

    Google Scholar 

  23. Jadoul M, El Akrout M, Cornu C, van Ypersele de Strihou C. Prevalence of hepatitis antibodies in healthcare workers [Letter]. Lancet 1994; 334: 339.

    Google Scholar 

  24. Forester G, Wormser GP, Adler S, Lebovics E, Calman M, O'Brien TA. Hepatitis C in health care setting. II. Seroprevalence among hemodialysis staff and patients in suburban New York City. AJIC 1993; 21: 5-8.

    Google Scholar 

  25. Alter MJ. Epidemiology of hepatitis C in the West. Semin Liver Dis 1995; 15: 5-14.

    Google Scholar 

  26. CDC. Recommendations for prevention and control of hepatitis C virus (HCV) infection and HCV-related chronic disease: MMWR 1998; 47(RR-19): 1-39.

  27. Moens G, Jacques P, Vranckx R. The seroprevalence of HCV-markers in a large sample of Belgian general hospital employees. The XV International Scientific Meeting of the International Epidemiological Association, Florence (Italy), 31 August-4 September, Abstract Book, Vol. 1, p. 257.

  28. De Brouwer C, Lecomte A. HCV antibodies in clinical health-care workers [Letter]. Lancet 1994; 344: 962.

    Google Scholar 

  29. Zuckerman J, Clewley G, Griffiths P, Cockroft A. Prevalence of hepatitis C antibodies in Clinical healthcare workers. Lancet 1994; 343: 1618-1620.

    Google Scholar 

  30. Neal KR, Dornan J, Irving WL. Prevalence of hepatitis C antibodies among health care workers of two teaching hospitals. Who is at risk? Br Med J 1997; 314: 179-180.

    Google Scholar 

  31. Olmsted RN. What is the risk of acquiring hepatitis C for health care workers and what are the recommendations for prophylaxis and follow-up after occupational exposure to hepatitis C virus? AJIC 1996; 24: 411-416.

    Google Scholar 

  32. Davis GL. Hepatitis C virus infection among healthcare workers. JAMA 1996; 275: 1474.

    Google Scholar 

  33. Sepkowitz KA. Occupationally acquired infections in health. Ann Intern Med 1996; 125: 917-922.

    Google Scholar 

  34. McQuillan G, Alter MJ, Moyer L, Lambert S, Margolis H. A population based serologic study of hepatitis C virus infection in United States (Abs). In: Proceedings of the IX International Symposium on Viral Hepatitis and Liver Disease. Rome, 1996: 8.

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Authors and Affiliations

  1. Educational and Clinical Epidemiology Unit, Pistoia, Italy

    C. Catalani

  2. Department of Statistics ‘G.Parenti’, University of Florence, Italy

    A. Biggeri & A. Gottard

  3. UO Infectious Diseases, Italy

    M. Benvenuti

  4. Immunohematology Service, Italy

    E. Frati

  5. Office of the Director, Pistoia Hospital, Italy

    C. Cecchini

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  1. C. Catalani
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  2. A. Biggeri
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  3. A. Gottard
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  4. M. Benvenuti
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  5. E. Frati
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  6. C. Cecchini
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Catalani, C., Biggeri, A., Gottard, A. et al. Prevalence of HCV infection among health care workers in a hospital in central Italy. Eur J Epidemiol 19, 73–77 (2004). https://doi.org/10.1023/B:EJEP.0000013250.54478.61

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  • DOI: https://doi.org/10.1023/B:EJEP.0000013250.54478.61

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