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Modification of Delayed Radiation-Induced Reactions of Duodenal Vessels and Mast Cells in Old Rats

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Abstract

Pronounced ultrastructural changes in vessels and mast cells were observed in duodenal lamina propria of Wistar rats 1 year after single whole-body γ-irradiation in a dose of 7.5 Gy. Inhibition of adrenocortical function with methopyrone reduced structural damage and improved animal survival.

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Authors and Affiliations

  1. Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk

    V. V. Popuchiev, L. N. Mikhina, N. D. Yakovleva, A. G. Konoplyannikov, V. V. Yuzhakov, E. A. Odintsova, R. A. Brodskii, L. E. Sevan'kaeva, K. Kita & I. Kita

  2. Institute of Industrial Organic Chemistry, Pschina, Poland

    V. V. Popuchiev, L. N. Mikhina, N. D. Yakovleva, A. G. Konoplyannikov, V. V. Yuzhakov, E. A. Odintsova, R. A. Brodskii, L. E. Sevan'kaeva, K. Kita & I. Kita

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  1. V. V. Popuchiev
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  2. L. N. Mikhina
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  3. N. D. Yakovleva
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  4. A. G. Konoplyannikov
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  5. V. V. Yuzhakov
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  6. E. A. Odintsova
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  7. R. A. Brodskii
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  8. L. E. Sevan'kaeva
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  9. K. Kita
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  10. I. Kita
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Correspondence to V. V. Popuchiev.

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Popuchiev, V.V., Mikhina, L.N., Yakovleva, N.D. et al. Modification of Delayed Radiation-Induced Reactions of Duodenal Vessels and Mast Cells in Old Rats. Bulletin of Experimental Biology and Medicine 136, 399–403 (2003). https://doi.org/10.1023/B:BEBM.0000010963.25058.a3

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  • DOI: https://doi.org/10.1023/B:BEBM.0000010963.25058.a3

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