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Recent advancements in ring closing olefin metathesis

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Abstract

A short overview on recent developments in ring closing metathesis (RCM) of 1,ω-dienes to cycloalkenes is provided, with particular emphasis on applications to natural product synthesis and the preparation of olfactory perfume ingredients. These examples show that RCM is becoming a mature tool for the formation of carbo– and heterocycles of any size ⩾ 5, including medium and large ring compounds which are difficult to prepare otherwise. Although the reactivity profile of the standard metathesis (pre)catalysts cannot be reduced to a simplistic picture, their excellent compatibility with an array of functional groups will be outlined.

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  1. Max–Planck–Institut für Kohlenforschung, Kaiser–Wilhelm–Platz 1, D–45470, Mülheim/Ruhr, Germany

    Alois Fürstner

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Fürstner, A. Recent advancements in ring closing olefin metathesis. Topics in Catalysis 4, 285–299 (1997). https://doi.org/10.1023/A:1019117012154

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