Abstract
Three aspects of integrated disease management are considered. The first is the epidemiological synergism that can be derived through combining management tactics, and through disease management at regional scales. Field studies with potato late blight are used to demonstrate epidemiological impacts of integrating host resistance, fungicides, host density, and host genetic diversity. The importance of considering spatial scale and regional disease management are demonstrated with examples of cultivar mixtures in three different pathosystems. The second aspect is the potential for integrated management to increase the durability of resistance, e.g., through reduction of pathogen population size and imposition of disruptive selection. At this point in time, most information on this topic is limited to arguments of logic and to the results of mathematical models; empirical data are largely lacking. We suggest that current theoretical approaches need to be supplemented with inclusion of more complex processes, such as the effect of fitness modifiers in pathogen populations and the influence of quantitative adaptation of pathogens to their hosts. The third aspect is integration of resistance into overall crop management, including factors such as the balance between yield potential and disease resistance and the management of genotype x environment interaction. Such integration will increase the likelihood that farmers will utilize durable resistance, and will be demonstrated with examples from wheat production in the Pacific Northwest region of the USA.
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Ahmed, H.U., C.C. Mundt & S.M. Coakley, 1995. Host-pathogen relationship of geographically diverse isolates of Septoria tritici and wheat cultivars. Plant Pathol 44: 838–847.
Ahmed, H.U., C.C. Mundt, M.E. Hoffer & S.M. Coakley, 1996. Selective influence of wheat cultivars on pathogenicity of Mycosphaerella graminicola (anamorph Septoria tritici). Phytopathology 86: 454–458.
Boeger, J.M., R.-S. Chen, & B.A. McDonald, 1993. Gene flow between geographic populations of Mycosphaerella graminicola (anamorph Septoria tritici) detected with restriction fragment length polymorphism markers. Phytopathology 83: 1148–1154.
Chen, R.-S., J.M. Boeger & B.A. McDonald, 1994. Genetic stability in a population of a plant pathogenic fungus over time. Mol Ecol 3: 209–218.
Chin, K.M. & M.S Wolfe, 1984. Selection on Erysiphe graminis in pure and mixed stands of barley. Plant Pathol 33: 535–546.
Cohan, F.M., E.C. King & P. Zawadzki, 1994. Amelioration of the deleterious pleiotropic effects of an adaptive mutation in Bacillus subtilis. Evolution 48: 81–95.
Cowger, C., M.E. Hoffer & C.C. Mundt, 2000. Specific adaptation by Mycosphaerella graminicola to a resistant wheat cultivar. Plant Pathol 49: 445–451.
Ferrandino, F.J., 1993. Dispersive epidemic waves: I. Focus expansion within a linear planting. Phytopathology 83: 795–802.
Garrett, K.A. & C.C. Mundt, 1999. Epidemiology in mixed host populations. Phytopathology 89: 984–990.
Garrett, K.A. & C.C. Mundt, 2000. Host diversity can reduce potato late blight severity for focal and general patterns of primary inoculum. Phytopathology 90: 1307–1312.
Garrett, K.A., R.J. Nelson, C.C. Mundt, G. Chacon, R.E. Jaramillo & G.A. Forbes, 2001. The effects of host diversity and other management components on epidemics of potato late blight in the humid highland tropics. Phytopathology 91: in press.
Kiyosawa, S., 1989. Breakdown of blast resistance in relation to general strategies of resistance gene deployment to prolong effectiveness of resistance in plants. In: K.J. Leonard & W.E. Fry (Eds.), Plant Disease Epidemiology, Vol. 2, pp. 251–283. McGraw-Hill, New York.
Kronstad, W.E., M.F. Kolding, P.K. Zwer & R.S. Karow, 1994. Registration of 'Gene' wheat. Crop Sci 34: 538.
Lannou, C. & C.C. Mundt, 1996. Evolution of a pathogen population in host mixtures. I. Study of the simple race-complex race equilibrium. Plant Pathol 45: 440–453.
Lannou, C. & C.C. Mundt, 1997. Evolution of a pathogen population in host mixtures: Rate of emergence of complex races. Theor Appl Genet 94: 991–999.
Leonard, K.J., 1977. Selection pressures and plant pathogens. Ann NY Acad Sci 277: 207–222.
Leonard, K.J. & R.J. Czochor, 1980. Theory of genetic interactions among populations of plants and their pathogens. Annu Rev Phytopathol 18: 237–258.
Levin, B.R., P. Veronique & N. Walker, 2000. Compensatory mutations, antibiotic resistance and the population genetics of adaptive evolution in bacteria. Genetics 154: 985–997.
Line, R.F. & X. Chen, 1995. Successes in breeding for and managing durable resistance in wheat rusts. Plant Dis 12: 1254–1255.
Marshall, D.R., 1989. Modeling the effects of multiline varieties on the population genetics of plant pathogens, In: K.J. Leonard & W.E. Fry (Eds.), Plant Disease Epidemiology, Vol. 2, pp. 284–317. McGraw-Hill, New York.
McDonald, B.A., C.C. Mundt & R.-S. Chen, 1996. The role of selection on the genetic structure of pathogen populations: Evidence from field experiments with Mycosphaerella graminicola on wheat. Euphytica 92: 73–80.
Minogue, K.P. & W.E. Fry, 1983. Models for the spread of disease: Model description. Phytopathology 73: 1168–1173.
Morrell, V., 1997. Antibiotic resistance: Road of no return. Science 278: 575–576.
Mundt, C.C., 1994. Use of host genetic diversity to control cereal diseases: Implications for rice blast, In: S.A. Leong, R.S. Zeigler & P.S. Teng (Eds.), Rice Blast Disease, pp. 293–307. CAB International, Wallingford (UK).
Mundt, C.C., 2002. Performance of wheat cultivars and cultivar mixtures in the presence of Cephalosporium stripe. Crop Prot 21: 91–99
Mundt, C.C. & L.S. Brophy, 1988. Influence of number of host genotype units on the effectiveness of host mixtures for disease control: A modeling approach. Phytopathology 78: 1087–1094.
Mundt, C.C., C. Cowger & M.E. Hoffer, 1999a. Disease management using variety mixtures. In: M. van Ginkel, A. McNab & J. Krupinsky (Eds.), Septoria and Stagonospora Diseases of Cereals: A Compilation of Global Research, pp. 111–116. CIMMYT, Mexico, D.F.
Mundt, C.C., M.E. Hoffer, H.U. Ahmed, S.M. Coakley, J.A. DiLeone & C. Cowger, 1999b. Population genetics and host resistance, In: J.A. Lucas, P. Bowyer & H.M. Anderson (Eds.), Septoria on Cereals: A Study of Pathosystems, pp. 115–130. CAB International, Wallingford (UK).
Parlevliet, J.E., 1981. Stabilizing selection in crop patho-systems: An empty concept or a reality? Euphytica 30: 259–269.
Parlevliet, J.E., 1989. Identification and evaluation of quantitative resistance, In: K.J. Leonard & W.E. Fry (Eds.), Plant Disease Epidemiology, Vol. 2, pp. 215–248. McGraw-Hill, New York.
Parlevliet, J.E. & A. van Ommeren, 1975. Partial resistance of barley to leaf rust, Puccinia hordei. II. Relationship between field trials, micro plot tests and latent period. Euphytica 24: 293–303.
Paysour, R.E. & W.E. Fry, 1983. Interplot interference: A model for planning field experiments with aerially disseminated pathogens. Phytopathology 73: 1014–1020.
Somasco, O.A., C.O. Qualset & D.G. Gilchrist, 1996. Single-gene resistance to Septoria tritici blotch in the spring wheat cultivar 'Tadinia'. Zeitschrift Pflanzen 115: 261–267.
van den Bosch, F., J.C. Zadoks & J.A.J. Metz, 1988. Focus expansion in plant disease. I. The constant rate of focus expansion. Phytopathology 78: 54–58.
Vanderplank, J.E., 1975. Principles of Plant Infection. Academic Press, New York.
Wolfe, M.S., 1985. The current status and prospects of multiline cultivars and variety mixtures for disease resistance. Annu Rev Phytopathol 23: 251–273.
Wolfe, M.S., 1992. Barley diseases: Maintaining the value of our varieties, In: L. Munck (Ed.), Barley Genetics VI, pp. 1055–1067. Munksgaard International Publishers, Copenhagen.
Zhu, Y., H. Chen, J. Fan, Y. Wang, Y. Li, J. Chen, J.-X. Fan, S. Yang, L. Hu, H. Leung, T.W. Mew, P.S. Teng, Z. Wang & C.C. Mundt, 2000. Genetic diversity and disease control in rice. Nature 406: 718–722.
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Mundt, C.C., Cowger, C. & Garrett, K.A. Relevance of integrated disease management to resistance durability. Euphytica 124, 245–252 (2002). https://doi.org/10.1023/A:1015642819151
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DOI: https://doi.org/10.1023/A:1015642819151