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Physiological controls of erythromycin production by Saccharopolyspora erythraea are exerted at least in part at the level of transcription

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Abstract

Erythromycin production by Saccharopolyspora erythraea is confined to the idiophase, derepressed by low initial glucose or phosphate concentration, and repressed when ammonium was used as nitrogen source. The idiophase limitation and effects of low phosphate or ammonium correlated with amounts of ery mRNA revealed by Northern blotting, indicating that they act at least partly at the transcriptional level. © Rapid Science Ltd. 1998

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Authors and Affiliations

  1. School of Biology, University of Leeds, Leeds, UK

    L.M. Reeve & S. Baumberg

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  1. L.M. Reeve
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  2. S. Baumberg
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Reeve, L., Baumberg, S. Physiological controls of erythromycin production by Saccharopolyspora erythraea are exerted at least in part at the level of transcription. Biotechnology Letters 20, 585–589 (1998). https://doi.org/10.1023/A:1005357930000

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