Abstract
This article introduces a CD-ROM containing whole-mount and histological images of normal growth and development of both the mouse mammary gland and the human breast. It also covers nonneoplastic lesions and neoplasias in both species including a catalog of lesions in genetically engineered mice. Instructions, with examples, on techniques such as whole-mount preparation, immunohistochemistry, in situ hybridization, and common histological stains are provided. The images are based on full-scale 1996 × 1640 pixel images at 300 pixels/inch and are annotated. Every genetically engineered model has one or more accompanying citations. Tables are provided for orientation and organization. The CD includes zoom capabilities, a search engine, and a help mode.
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REFERENCE
R. D. Cardiff, R. A. Anver, B. A. Gusterson, L. Heninghausen, R. A. Jensen, M. J. Merino, S. Rehm, J. Russo, F. A. Tavassoli, L. M. Wakefield, J. M. Ward, and J. E. Green (2000). The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis Meeting. Oncogene 19:968–988.
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Cardiff, R.D., Wagner, U. & Henninghausen, L. Mammary Cancer in Humans and Mice: A Tutorial for Comparative Pathology. The CD-ROM. J Mammary Gland Biol Neoplasia 5, 243–244 (2000). https://doi.org/10.1023/A:1026451607575
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DOI: https://doi.org/10.1023/A:1026451607575