Abstract
The influence of zosterin-pectin of the seagrass Zostera marina on the content of DNA and RNA in rat hepatocytes under normal conditions and with lead contamination has been studied. It was shown that zosterin increases the share of the high-ploidy (8c) nuclei and the content of the nuclear RNA of the intact animals and, against a background of toxicant action, normalizes the ratio of the ploidy classes and further increases the RNA mass.
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REFERENCES
Anisimov, A.P., Simple Method to Obtain Constant (Permanent) Crushed Preparations Using a Cellophane, Tsitologiya, 1992, vol. 34, no. 11/12, pp. 110-112.
Batyrshina, G.F., A Perspective of Using Antioxidants for Reparative Regeneration, Morphology: Abstracts of Reports of V Congr. Internat. Assoc. Morphol., 2000, vol. 117, no. 3, pp. 19-20.
Brodsky, V.Ya. and Uryvaeva, I.V., Kletochnaya poliploidiya. Proliferatsiya i differentsirovka (Cellular Polyploidy. Proliferation and Differentiation), Moscow: Nauka, 1981.
Evtanaziya eksperimental'nykh zhivotnykh (metodicheskie rekomendatsii po vyvedeniyu zhivotnykh iz eksperimenta) (Euthanasia of experimental animals (Methodical Recommendations on Removing Animals from the Experiment)), Moscow: Meditsina, 1985.
Ibragimova, I.F., Danilov, R.K., and Zagidullin, S.Z., Proliferation, Differentiation and Death of Cardiomyocytes on Action of Antioxidant, Morfologiya, 1997, vol. 112, no. 5, pp. 50-54.
Khasina, E.I., Bezdetko, G.N., and Yankova, V.I., ProtectiveAction of Zosterin in the Case of Experimental Toxic Affection of a Liver, Byull. SO AMN, 1998, no. 1, pp. 51-55.
Khasina, E.I., Trebukhov, E.E., and Zolotukhina, O.N., Optimization of Physical Working Capacity Using Zosterin, Dal'nevost. Med. Zhurn., 2001, no. 2, pp. 45-48.
Levina, E.N., Obshchaya toksikologiya metallov (General Toxicology of Metals), Moscow: Meditsina, 1972.
Lilly, R., Patogistologicheskaya tekhnika i prakticheskaya gistokhimiya (Pathohistologic Technique and Practical Histochemistry), Moscow: Mir, 1969.
Loyenko, Yu.N., Artyukov, A.A., Kozlovskaya, E.P., et al., Zosterin, Zosterin, Vladivostok: Dal'nauka, 1997.
Mamyrbaeva, Z.Zh., Bersimbaev, R.I., Shalakhmetova, G.M., et al., The Levels of Polyploidization and Hypertrophy of the Hepatocytes of Rats at Different Periods of Ontogenesis Under Normal Conditions and the Chronic Action of Cadmium Sulphate and Strontium Chloride, Tsitologiya, 1997, vol. 39, no. 1, p. 80.
Meerson, F.Z., Common Adaptation Mechanism and the Role of Stress Response, Basic Stages of the Process, Fiziologiya adaptatsionnykh protsessov (Physiology of the Adaptation Processes), Moscow: Nauka, 1986, pp. 77-123.
Ryabinina, Z.A. and Benyush, V.A., Poliploidiya i gipertrofiya kletok v protsessakh rosta i vosstanovleniya (Polyploidy and Hypertrophy of Cells in the Processes of Growth and Restoration), Moscow: Meditsina, 1973.
Sakuta, G.A., Kudryavtseva, M.V., and Kudryavtsev, B.N., Interconnection of the Hepatocyte Nuclei Polyploidization with the Synthetic Processes in the Course of Regeneration of Cirrhotic Liver in Rats, Tsitologiya, 1993, vol. 35, no. 10, p. 91.
Tverskoi, L.A., Shalimov, S.A., and Keisevich, L.V., Therapeutic and Therapeutic-Prophylactic Action of Pectin, Vracheb. delo, 1995, nos. 9–12, pp. 10-16.
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Sgrebneva, M.N., Anisimov, A.P. & Khasina, E.I. Influence of Pectin from the Seagrass Zostera marina on the Content of DNA and RNA in Rat Hepatocytes Contaminated by Lead. Russian Journal of Marine Biology 28, 352–354 (2002). https://doi.org/10.1023/A:1020919804439
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DOI: https://doi.org/10.1023/A:1020919804439