Skip to main content
SpringerLink
Log in

1H NMR Quantification of poly(Ethylene Glycol)-Phosphatidylethanolamine in Phospholipid Mixtures

  • Published:
Pharmaceutical Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

REFERENCES

  1. M. C. Woodle and D. D. Lasic. Sterically stabilized liposomes. Biochim. Biophys. Acta 1113:171–199 (1992).

    Google Scholar 

  2. G. Storm, S. O. Belliot, T. Daemen, and D. D. Lasic. Surface modification of nanoparticles to oppose uptake by the mononuclear phagocytic system. Adv. Drug Del. Rev. 17:31–48 (1995).

    Google Scholar 

  3. M. C. Woodle and G. Storm (Eds.) Long Circulating Liposomes: Old Drugs, New Therapeutics, Springer Verlag, 1998.

  4. G. Storm, M. T. ten Kate, P. K. Working, and I. A. J. M. Bakker-Woudenberg. Doxorubicin entrapped in sterically stabilized liposomes: effects on bacterial blood clearance capacity of the mononuclear phagocyte system. Clin. Cancer Res. 3:111–115 (1998).

    Google Scholar 

  5. I. A. J. M. Bakker-Woudenberg, A. F. Lokerse, M. T. ten Kate, J. W. Mouton, M. C. Woodle, and G. Storm. Liposomes with prolonged blood circulation and selective localization in Klebsiella pneumonia-infected lung tissue. J. Infect. Dis. 168:164–171 (1993).

    Google Scholar 

  6. O. C. Boerman, W. J. G. Oyen, L. van Bloois, E. B. Koenders, J. W. M. van der Meer, F. H. M. Corstens, and G. Storm. Optimization of technetium-99m-labeled PEG liposomes to image focal infection: effects of particle size and circulation time. J. Nucl. Med. 38:489–493 (1997).

    Google Scholar 

  7. N. J. M. Birdsall, J. Feeney, A. G. Lee, Y. K. Levine, and J. C. Metcalfe. Dipalmitoyl-lecithin: assignment of the 1H and 13C nuclear magnetic resonance spectra, and conformational studies. J. Chem. Soc., Perkin Trans. 2:1441–1445 (1972).

    Google Scholar 

  8. R. D. Hershberg, G. H. Reed, A. J. Slotboom, and G. H. de Haas. Nuclear magnetic resonance studies of the aggregation of dihexanoyllecithin and of diheptanoyllecithin in aqueous solutions. Biochim. Biophys. Acta 424:73–81 (1976).

    Google Scholar 

  9. D. Marsh and A. Watts. NMR spin-spin splittings in lipid membranes. FEBS Lett. 85:124–126 (1978).

    Google Scholar 

  10. H. Hauser, W. Guyer, I. Pascher, P. Skrabal, and S. Sundell. Polar group conformation of phosphatidylcholine. Effect of solvent and aggregation. Biochemistry 19:366–373 (1980).

    Google Scholar 

  11. X. Han, X. Chen, and R. W. Gross. Chemical and magnetic inequivalence of glycerol protons in individual subclasses of choline glycerophospholipids: implications for subclass-specific changes in membrane conformational states. J. Am. Chem. Soc. 113:7104–7109 (1991).

    Google Scholar 

  12. E. G. Bligh and W. J. Dyer. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37:911–917 (1959).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmaceutics, Faculty of Pharmacy, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, PO Box 80 082, 3508 TB, Utrecht, The Netherlands. To whom correspondence should be addressed

    E. A. A. M. Vernooij & D. J. A. Crommelin

  2. Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Center for Biopolymers at Interfaces, Biomedical Polymers Research Building, RM 108, Salt Lake City, Utah, U.S.A, 84112-9450

    C. A. Gentry & J. N. Herron

  3. Department of Pharmaceutical Analysis, Faculty of Pharmacy, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, PO Box 80 082, 3508 TB, Utrecht, The Netherlands

    J. J. Kettenes-van den Bosch

Authors
  1. E. A. A. M. Vernooij
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. A. Gentry
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. N. Herron
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. J. A. Crommelin
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. J. Kettenes-van den Bosch
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. A. A. M. Vernooij.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vernooij, E.A.A.M., Gentry, C.A., Herron, J.N. et al. 1H NMR Quantification of poly(Ethylene Glycol)-Phosphatidylethanolamine in Phospholipid Mixtures. Pharm Res 16, 1658–1661 (1999). https://doi.org/10.1023/A:1011937511806

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1011937511806

Search

Navigation