Abstract
The results of a comprehensive study of blood rheology in subjects with a normal or changed vascular bed show that chronic venous and arterial insufficiency in the lower limbs, caused by morphological changes in vessels, is accompanied by a decrease in the blood fluidity. This impairs the efficiency of oxygen supply to tissues. The authors detected rheological shifts that facilitate increases in the blood viscosity.
Similar content being viewed by others
REFERENCES
Chernukh, A.M., Aleksandrov, P.N., and Alekseev, O.V., Mikrotsirkulyatsiya (Microcirculation), Moscow: Meditsina, 1984.
Seleznev, S.A., Nazarenko, G.I., and Zaitsev, V.S., Klinicheskie aspekty mikrogemotsirkulyatsii (Clinical Aspects of Microhemocirculation), Leningrad: Meditsina, 1985.
Fahraeus, R., The Viscosity of the Blood in Narrow Capillary Tubes, Am. J. Physiol., 1931, vol. 96, p. 562.
Rosenblatt, G., Stokes, J., and Bassett, D., Whole Blood Viscosity, Hematocrit and Serum Lipid Levels in Normal Subjects and Patients with Coronary Heart Disease, J. Lab. Clin. Med., 1965, vol. 62, no. 2, p. 203.
Tsarev, O.A., Application of Chronic Normovolemic Hemodilution in Correcting Hemorheological Disturbances in Patients with Obliterative Arterial Diseases, Angiol. Sosud. Khirurg., 1997, no. 2 (Suppl.), p. 125.
Price, J.F., Mowbray, P.I., Lee, A.J., et al., Relationship between Smoking and Cardiovascular Risk Factors in the Development of Peripheral Arterial Disease and Coronary Artery Disease, Eur. Heart J., 1999, vol. 20, no. 5, p. 344.
Le Devehat, C., Khodabandehlou, T., Vimeux, M., et al., The Effects of Cyclo 3 Fort Treatment on Hemorheological Disturbances during Venous Stasis in Patients with Chronic Venous Insufficiency, Microcirc. Clin. Exper., 1994, vol. 14, p. 165.
Thomas, P.R.S., Nash, G.B., and Dormandy, J.A., White Cell Accumulation in Dependent Legs of Patients with Venous Hypertension: A Possible Mechanism for Trophic Changes in the Skin, Br. Med. J., 1988, vol. 296, p. 1693.
Dintenfass, L., Red Cell Rigidity, “Tk,” and Filtration, Clin. Hemorheol., 1985, no. 5, p. 241.
Stoltz, J.F., Donner, M., and Muller, S., Hemorheology in Practice: An Introduction to the Concept of a Hemorheological Profile, Rev. Port. Hemorheol., 1991, vol. 5, p. 175.
Ashkinazi, I.Ya., Red Cell Aggregation and Thromboplastin Formation, Byull. Eksp. Biol. Med., 1972, vol. 74, no. 7, p. 29.
MacGregor, R.R., Granulocyte Adherence Change Induced by Hemodialysis, Endotoxin Apinephrine and Glucocorticoids, Ann. Intern. Med., 1977, vol. 86, p. 35.
Mayer, G.A., Fridrich, I., Newell, J., et al., Plasma Components and Blood Viscosity, Biorheology, 1966, vol. 3, no. 4, p. 177.
Rampling, M.W., Red Cell Aggregation as a Risk Factor for Thrombosis, Rev. Port. Hemorheol., 1991, vol. 5, p. 39.
Dormandy, J.A., Microcirculation and Venous Ulcers in Lower Limbs, Flebolimfologiya, 1997, no. 5, p. 4.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gushchin, A.G., Murav'ev, A.V., Shaechkina, I.K. et al. Hemorheological Status of a Body with a Normal vs. Changed Vascular Bed. Human Physiology 27, 458–460 (2001). https://doi.org/10.1023/A:1010919020982
Issue Date:
DOI: https://doi.org/10.1023/A:1010919020982