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Enhanced activity of Candida rugosa lipase modified by polyethylene glycol derivatives

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Abstract

The derivatives of polyethylene glycol (PEG) were prepared by reacting PEG with propylene oxide to enhance its hydrophobicity and introduce a branched structure. The PEG derivatives were activated with cyanuric chloride and used to modify the lipase fromCandida rugosa. The maximum specific activity of lipase modified with the PEG derivatives was about 2-fold of that modified with PEG for the esterification of oleic acid and lauryl alcohol in hexane.

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Authors and Affiliations

  1. Chemical Engineering Research Center, Tianjin University, Tianjin, 300072, P.R. China

    J.C. Wu, G.F. Zhang & Z.M. He

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  1. J.C. Wu
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  2. G.F. Zhang
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  3. Z.M. He
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Correspondence to J.C. Wu.

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Wu, J., Zhang, G. & He, Z. Enhanced activity of Candida rugosa lipase modified by polyethylene glycol derivatives. Biotechnology Letters 23, 211–214 (2001). https://doi.org/10.1023/A:1005675807353

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