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Crystal and molecular structure of fenspiride, C15H20N2O2

Published online by Cambridge University Press:  14 April 2020

Silvina Pagola Open the ORCID record for Silvina Pagola [Opens in a new window]
Silvina Pagola*
Affiliation:
Department of Chemistry and Biochemistry, Old Dominion University, 4402 Elkhorn Avenue, Norfolk, Virginia23529, USA College of Science Major Instrumentation Cluster (COSMIC) Laboratory, Norfolk, Virginia23529, USA
*
a)Author to whom correspondence should be addressed. Electronic mail: spagola@odu.edu
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Abstract

The crystal and molecular structure of fenspiride, a bronchodilator and anti-inflammatory drug, are reported. Fenspiride crystallizes in the monoclinic system, with two crystallographically independent molecules in the general position of the space group P21/n (No. 14) and Z = 8. Rietveld refined unit cell parameters are a = 11.52013(8) Å, b = 5.614091(31) Å, c = 44.1567(4) Å, α = 90°, β = 93.0885(6)°, γ = 90°, and V = 2851.69(4) Å3.

Keywords

X-ray powder diffractioncrystal structure solution from powdersRietveld refinementpharmaceuticalsfenspiride
Type
Rapid Communication
Information
Powder Diffraction , Volume 35 , Issue 2 , June 2020 , pp. 144 - 146
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Copyright
Copyright © International Centre for Diffraction Data 2020

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