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Gene expression and mental disease1

Published online by Cambridge University Press:  09 July 2009

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Abstract

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Editorial
Copyright
Copyright © Cambridge University Press 1989

References

Anderton, B. H. (1988). Alzheimer's disease paired helical filaments and the cytoskeleton. Nature 335, 497498.CrossRefGoogle ScholarPubMed
Bahmanyar, S.Higgins, G. A., Goldgaber, D., Lewis, D. A., Morrison, J H., Wilson, M. C., Shankar, S. K. & Gadjusek, D. C. (1987) Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease. Science 237, 7780.CrossRefGoogle ScholarPubMed
Baron, M. & Rainer, J. D. (1988). Molecular genetics and human disease implications for modern psychiatric research and practice. British Journal of Psychiatry 152. 741753CrossRefGoogle ScholarPubMed
Bowen, D. M. (1988). Neurotransmitters in Alzheimer's disease. Age 11. 104110Google Scholar
Breitbart, R. E.Andreadis, A & Nadel-Ginard, B. (1987). Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes. Annual Review of Biochemistry 56, 467495.CrossRefGoogle ScholarPubMed
Carroll, R W. (1988). Alzheimer's disease: enter a protease inhibitor. Nature 331, 478479CrossRefGoogle Scholar
Chaudhari, N. & Hahn, W. E. (1983) Genetic expression in the developing brain. Science 220, 924928.CrossRefGoogle ScholarPubMed
Chikharaishi, D. M. (1986). The ID, brain identifier, model of neuronal gene expression: a re-evaluation. Trends in Neuroscience 9, 543546.Google Scholar
Cohen, M. L., Golde, T. E., Usiak, M. F., Younkin, L H. & Younkin, S. G. (1988). In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer's disease. Proceedings of the National Academy of Sciences USA 85, 12271231.CrossRefGoogle Scholar
Crapper McLachlan, D. R., Lukiw, W. J., Wong, L., Bergeron, C. & Bech-Hansen, N. T. (1988). Selective messenger RNA reduction in Alzheimer's disease. Molecular Brain Research 3, 255262.CrossRefGoogle Scholar
Darnell, J. E. (1982). Variety in the level of gene control in eukaryotic cells. Nature 297, 365371.Google Scholar
Friedman, R. L., Manly, S. P., McMahon, M., Kerr, I. M. & Stark, G. R. (1984) Transcriptional and posttranscriptional regulation of interferon-induced expression in human cells. Cell 38, 745755.CrossRefGoogle ScholarPubMed
Gandy, S.Czernik, A. J. & Greengard, P. (1988). Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca++ / calmodulin-dependent protein kinase II. Proceedings of the National Academy of Sciences USA 85, 62186221CrossRefGoogle Scholar
Gilbert, J. M., Brown, B. A., Strocchi, P., Bird, E. D. & Marotta, C. A. (1981). The preparation of biologically active mRNA from human post mortem brain tissue. Journal of Neurochemislry 36, 976984.CrossRefGoogle Scholar
Goedert, M. (1987). Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease. EM BO Journal 6, 36273632.Google ScholarPubMed
Guillemotte, J. G., Wong, L., Crapper McLachlan, D. R. & Lewis, P. N. (1986) Characterization of messenger RNA from the cerebral cortex of control and Alzheimer-afflicted brain. Journal of Neurochemislry 47, 987997.CrossRefGoogle Scholar
Harrison, P J. (1986). The pathogenesis of Alzheimer's disease. beyond the cholinergic hypothesis Journal of the Royal Society of Medicine 79, 347351.CrossRefGoogle ScholarPubMed
Higgins, G A., Lewis, D. A., Bahmanyar, S., Goldgaber, D., Gadjusek, D. C., Young, W G., Morrison, J. H. & Wilson, M. C. (1988) Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease. Proceedings of the National Academy of Sciences USA 85, 12971301.CrossRefGoogle ScholarPubMed
Hunt, T. (1988). Tubulin synthesis controlling mRNA lifespan. Nature 334, 567568.CrossRefGoogle Scholar
Jeste, D. V., Lohr, J. B. & Goodwin, F. K. (1988). Neuroanatomical studies of major affective disorders: a review and suggestions for further research. British Journal of Psychiatry 153, 444459.CrossRefGoogle ScholarPubMed
Johnson, S. A., Morgan, D. G. & Finch, C. E. (1986). Extensive post mortem stability of RNA from rat and human brain. Journal of Neuroscience Research 16, 267280.CrossRefGoogle Scholar
Larkfors, L., Ebendal, T., Whittemore, S. R., Persson, H., Hoffer, B. & Olson, L (1987). Decreased level of nerve growth factor (NGF) and its messenger RNA in the aged rat brain. Molecular Brain Research 3, 5560.CrossRefGoogle Scholar
Lewin, B. (1985). Genes II. Wiley. New York.Google Scholar
Lewis, D. A., Higgins, G. A., Young, W. G., Goldgaber, D., Gadjusek, D. C & Wilson, M. C. (1988). Distribution of precursor amyloid-beta-protein messenger RNA in human cerebral cortex: relationship to neurofibrillary tangles and neuntic plaques. Proceedings of the National Academy of Sciences USA 85, 16911695.CrossRefGoogle ScholarPubMed
Magee, T. & Hanley, M. (1988). Protein modification: sticky fingers and CAAX boxes. Nature 335, 114115.CrossRefGoogle ScholarPubMed
Majocha, R. E., Benes, F M., Reifel, J. L., Rodenrys, A. M. & Marotta, C. A. (1988). Laminar-specific distribution and infrastructural detail of amyloid in the Alzheimer disease cortex visualized by computer-enhanced imaging of epitopes recognized by monoclonal antibodies Proceedings of the National Academy of Sciences USA 85, 61826186.CrossRefGoogle ScholarPubMed
Mann, D. M. A., Neary, D., Yates, P. O., Lincoln, J., Snowden, J. S & Stanworth, P. (1981). Alterations in protein synthetic capability of nerve cells in Alzheimer's disease Journal of Neurology, Neurosurgery and Psychiatry 44, 97102.CrossRefGoogle ScholarPubMed
Marotta, C. A., Majocha, R E., Coughlin, J. F., Manz, H. J., Davies, P., Ventosa-Michelman, M., Chou, W.-G., Zain, S. B. & Sajdel-Sulkowska, E. M. (1986). Transcriptional and translational regulatory mechanisms during normal aging of the mammalian brain and in Alzheimer's disease. Progress in Brain Research 70, 303320.CrossRefGoogle ScholarPubMed
Miller, C A, Rudnicka, M., Hinton, D. R., Blanks, J. C. & Kozlowski, M. (1987). Monoclonal antibody identification of subpopulations of cerebral cortical neurons affected in Alzheimer disease. Proceedings of the National Academy of Sciences USA 84, 86578661.CrossRefGoogle ScholarPubMed
Milner, R. J., Bloom, F. E. & Sutcliffe, J. G. (1987). Brain-specific genes: strategies and issues. Current Topics in Developmental Biology 21, 117150.CrossRefGoogle Scholar
Octave, J. N., de Sauvage, F., Macq, A. F. & Maloteaux, J. M. (1988). Cloning of the cDNA from normal brain and brain of patients with Alzheimer's disease in the expression vector lambda GT 11. Progress in Neuropsychopharmacology and Biological Psychiatry 12, 813820.CrossRefGoogle ScholarPubMed
Owen, M. J., Whatley, S. J. (1988). Polymorphic DNA markers and mental disease. Psychological Medicine 18, 529533.CrossRefGoogle ScholarPubMed
Palmert, M. R., Golde, T. E., Cohen, M. L., Kovacs, D. M., Tanzi, R. E., Gusella, J. F., Usiak, M. F., Younkin, L. H. & Younkin, S. G. (1988). Amyloid protein messenger RNAs: differential expression in Alzheimer's disease Science 241, 10801084.Google Scholar
Pearson, R. C. A., Esiri, M. M, Hiorns, R. W., Wilcock, G. K. & Powell, T. P. S. (1985). Anatomical correlates of the pathological changes in the neocortex of Alzheimer's disease. Proceedings of the National Academy of Sciences USA 82, 45314534.Google Scholar
Perrett, C. W., Marchbanks, R. M. & Whatley, S. A. (1988). Characterisation of messenger RNA extracted post-mortem from the brains of schizophrenic, depressed and control subjects. Journal of Neurology, Neurosurgery and Psychiatry 51, 325331.CrossRefGoogle ScholarPubMed
Perry, E. K. (1988). Acetylcholine and Alzheimer's disease. British Journal of Psychiatry 152, 737740.CrossRefGoogle ScholarPubMed
Perry, E. K.. Perry, R. H. & Tomlinson, B E (1982). The influence of agonal status on some neurochemical activities of post mortem human brain tissue. Neuroscience Letters 29, 303307CrossRefGoogle Scholar
Podinsky, M. B.. Lee, G. & Selkoe, D. J (1987) Gene dosage of the amyloid beta precursor protein in Alzheimers disease. Science 238, 669671Google Scholar
Ptashne, M (1988). How eukaryotic transcriptional activators work. Nature 335, 683689.Google Scholar
Rennert, P. D & Heinrich, G. (1986). Nerve growth factor mRNA in brain: localization by in situ hybridization. Biochemical and Biophysical Research Communications 138, 813818CrossRefGoogle ScholarPubMed
Reynolds, G. P. (1988). Post-mortem neurochemistry of schizophrenia. Psychological Medicine 18, 793797.CrossRefGoogle ScholarPubMed
Roberts, G. W. (1988). Abnormalities in brain structure in schizophrenia. Current Opinion in Psychiatry 1, 8389.Google Scholar
St George Hyslop, P. H., Tanzi, R. E., Polinsky, R. J., Neve, R. L, Pollen, D., Drachman, D., Growdon, J., Cupples, L. A., Nee, L., Myers, R H., O'Sullivan, D., Watkins, P. C., Amos, J. A., Deutsch, C. A., Bodfish, J. W., Kinsbourne, M., Feldman, R. G., Brum, A, Amaducci, L., Foncin, J.-F & Gusella, J. F (1987). Absence of duplication of chromosome 21 genes in familial and sporadic Alzheimer's disease. Science 238, 664666.CrossRefGoogle ScholarPubMed
Sajdel-Sulkowska, E. M. & Marotta, C. A. (1984). Alzheimer's disease brain: alterations in RNA levels and in a ribonuclease-inhibitor complex. Science 225, 947949.CrossRefGoogle Scholar
Schlief, R. (1988) DNA binding by proteins Science 241, 11821187.CrossRefGoogle Scholar
Sutclifle, J. G. (1988). mRNA in the mammalian central nervous system. Annual Review of Neuroscience 11, 157198.CrossRefGoogle Scholar
Tanzi, R. E., Bird, E. D., Latt, S. A. & Neve, R. L. (1987). The amyloid beta protein gene is not duplicated in brains from patients with Alzheimer's disease Science 238, 666669.CrossRefGoogle Scholar
Valentino, K. L., Eberwine, J. H. & Barchas, J. D., (eds.) (1987). In situ Hybridization: Applications to Neurobiology Oxford University Press: New York.Google Scholar
Weatherall, D. (1987). Molecular and cell biology in clinical medicine: introduction. British Medical Journal 295, 587589.CrossRefGoogle ScholarPubMed
Worley, P. F., Baraban, J. M. & Snyder, S H. (1987). Beyond receptors: multiple second-messenger systems in brain. Annals of Neurology 21, 217229.CrossRefGoogle ScholarPubMed
Yanofsky, C. (1988). Transcription attenuation. Journal of Biological Chemistry 263, 609612.CrossRefGoogle ScholarPubMed
Yen, T. J., Machlin, P. S. & Cleveland, D. W. (1988). Autoregulated instability of beta-tubulin mRNAs by recognition of the nascent amino-acid terminus of beta-tubulin. Nature 334, 580585.CrossRefGoogle ScholarPubMed