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Seeing the fetus from a DOHaD perspective: discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress

Part of: Advance Imaging in DOHaD

Published online by Cambridge University Press:  21 September 2020

Janna L. Morrison Open the ORCID record for Janna L. Morrison [Opens in a new window] ,
Oyekoya T. Ayonrinde ,
Alison S. Care ,
Geoffrey D. Clarke Open the ORCID record for Geoffrey D. Clarke [Opens in a new window] ,
Jack R.T. Darby Open the ORCID record for Jack R.T. Darby [Opens in a new window] ,
Anna L. David Open the ORCID record for Anna L. David [Opens in a new window] ,
Justin M. Dean ,
Stuart B. Hooper ,
Marcus J. Kitchen  and
Christopher K. Macgowan
...Show all authors
Janna L. Morrison*
Affiliation:
Early Origins of Adult Health Research Group, Health and Biomedical Innovation, UniSA: Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia
Oyekoya T. Ayonrinde
Affiliation:
Fiona Stanley Hospital, Murdoch, WA, Australia Medical School, The University of Western Australia, Perth, WA, Australia
Alison S. Care
Affiliation:
The Robinson Research Institute and Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia
Geoffrey D. Clarke
Affiliation:
Department of Radiology, University of Texas Health Science Center, San Antonio, TX, USA
Jack R.T. Darby
Affiliation:
Early Origins of Adult Health Research Group, Health and Biomedical Innovation, UniSA: Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia
Anna L. David
Affiliation:
Elizabeth Garrett Anderson Institute for Women’s Health, University College London, London, UK
Justin M. Dean
Affiliation:
Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
Stuart B. Hooper
Affiliation:
The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia The Department of Obstetrics and Gynecology, Monash University, Melbourne, Victoria, Australia
Marcus J. Kitchen
Affiliation:
School of Physics and Astronomy, Monash University, Melbourne, Victoria, Australia
Christopher K. Macgowan
Affiliation:
Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
Andrew Melbourne
Affiliation:
School of Biomedical Engineering and Imaging Sciences, Kings College London, London, UK
Erin V McGillick
Affiliation:
The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia The Department of Obstetrics and Gynecology, Monash University, Melbourne, Victoria, Australia
Charles A. McKenzie
Affiliation:
Department of Medical Biophysics, Western University, London, ON, Canada Lawson Health Research Institute and Children’s Health Research Institute, London, ON, Canada
Navin Michael
Affiliation:
Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore
Nuruddin Mohammed
Affiliation:
Maternal Fetal Medicine Unit, Department of Obstetrics and Gynecology, Aga Khan University Hospital, Karachi, Pakistan
Suresh Anand Sadananthan
Affiliation:
Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore
Eric Schrauben
Affiliation:
Translational Medicine, Hospital for Sick Children, Toronto, ON, Canada
Timothy R.H. Regnault
Affiliation:
Lawson Health Research Institute and Children’s Health Research Institute, London, ON, Canada Department of Obstetrics and Gynecology, Western University, London, ON, Canada Department of Physiology and Pharmacology, Western University, London, ON, Canada
S. Sendhil Velan
Affiliation:
Singapore Bioimaging Consortium, Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore Singapore Institute for Clinical Sciences, Agency for Science, Technology, and Research (A*STAR), Singapore, Singapore
*
Address for correspondence: Janna L. Morrison, Early Origins of Adult Health Research Group, Health and Biomedical Innovation, UniSA: Clinical and Health Sciences, University of South Australia, AdelaideGPO 2471, SA, Australia. Email: janna.morrison@unisa.edu.au
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Abstract

Advanced imaging techniques are enhancing research capacity focussed on the developmental origins of adult health and disease (DOHaD) hypothesis, and consequently increasing awareness of future health risks across various subareas of DOHaD research themes. Understanding how these advanced imaging techniques in animal models and human population studies can be both additively and synergistically used alongside traditional techniques in DOHaD-focussed laboratories is therefore of great interest. Global experts in advanced imaging techniques congregated at the advanced imaging workshop at the 2019 DOHaD World Congress in Melbourne, Australia. This review summarizes the presentations of new imaging modalities and novel applications to DOHaD research and discussions had by DOHaD researchers that are currently utilizing advanced imaging techniques including MRI, hyperpolarized MRI, ultrasound, and synchrotron-based techniques to aid their DOHaD research focus.

Keywords

DOHaDfetusMRIultrasoundsynchrotron
Type
Review
Information
Journal of Developmental Origins of Health and Disease , Volume 12 , Issue 2 , April 2021 , pp. 153 - 167
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Copyright
© The Author(s), 2020. Published by Cambridge University Press in association with International Society for Developmental Origins of Health and Disease

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