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The formation of Hfr strains in Escherichia coli K12

Published online by Cambridge University Press:  14 April 2009

Paul Broda
Paul Broda
Affiliation:
Medical Research Council, Microbial Genetics Research Unit, Hammersmith Hospital, London W.12*
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The isolation and characterization of an isogenic series of twelve Hfr strains is described. From their points of origin it was concluded that the sex factor integrates at a limited number of sites on the bacterial chromosome. Although the nutritional requirements of these Hfr strains were similar to those of the parent F+ strain, it was observed that one group had a markedly slower growth rate. The relevance of these observations to theories on the nature of F+ fertility and on the formation of Hfr strains is discussed.

Type
Research Article
Information
Genetics Research , Volume 9 , Issue 1 , February 1967 , pp. 35 - 47
Copyright
Copyright © Cambridge University Press 1967

References

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