Fecal microbiota transplantation for recurrent Clostridium difficile infection in children
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The Development of Early Life Microbiota in Human Health and Disease
2022, EngineeringCitation Excerpt :Fecal microbiota transplantation (FMT) is a well-tolerated, simple, and promising treatment for pediatric diseases. FMT has been performed to treat pediatric diseases such as ASD [223], IBD [224], Clostridium difficile infection [225], and refractory diarrhea [226]. In line with findings in adults, the symptoms of two-year-old children with Clostridium difficile infection were relieved by FMT and showed no recurrence within six months of follow-up [225].
Clostridium difficile Infection in Children
2019, Advances in PediatricsCitation Excerpt :However, it has not been shown that the route affects the efficacy of FMT. Adverse events are uncommon, and include gastrointestinal symptoms (eg, nausea, vomiting, flatulence, bloating, abdominal and/or rectal discomfort), headaches, and transient fever [67–69]. There are no published RCTs in children and the experience, although limited, is increasing.
Therapeutic Contraindications in Exotic Pets
2018, Veterinary Clinics of North America - Exotic Animal PracticeCitation Excerpt :Metronidazole (20 mg/kg orally or IV every 12 h) can be administered for clostridial overgrowth and has been reported to reduce the number of mortalities associated with enterotoxemia.66 The re-establishment of normal colonic microbiome through fecal microbiota transplantation has an inhibitory effect against pathogenic bacteria and is now considered a standard treatment of recurrent C difficile infections in humans.67 Based on this principle, anecdotal reports of transfaunation with cecotrophes from a healthy conspecific show that this treatment may be of benefit in rabbits with antibiotic-associated dysbiosis.68
Faecal microbiota transplantation in children: A systematic review
2024, Acta Paediatrica, International Journal of PaediatricsColonic Endoscopic Tubing Is Safe and Effective Approach for Washed Microbiota Transplantation in Autistic Children
2023, Gastroenterology Research and PracticeDetection of Newly Secreted Antibodies Predicts Nonrecurrence in Primary Clostridioides difficile Infection
2022, Journal of Clinical Microbiology