Transmission and Epidemiology of Helicobacter pylori

https://doi.org/10.1016/S0002-9343(96)80224-5Get rights and content

Helicobacter pylori is one of the most common bacterial infections worldwide. However, the majority of those infected do not develop clinical manifestations of disease. This review discusses the epidemiology of the organism in terms of incidence and prevalence, the presumed means of transmission from person to person, and how typing of the organism has helped the epidemiologist. The epidemiology of disorders that are associated with H. pylori is also discussed.

References (47)

  • NS Akopyants et al.

    Cagll, a new multigene locus associated with virulence m Helicobacter pylori

    Gut.

    (1995)
  • N Lange et al.
  • JG Fox et al.

    High prevalence and persistence of cytotoxin-positive Helicobacter pylori strains in a population with high prevalence of atrophic gastritis

    Am J Gastroenterol.

    (1992)
  • Epidemiology of, and risk factors for, Helicobacter pylori infection among 3194 asymptomatic subjects in 17 populations. The Eurogast Study Group

    Gut

    (1993)
  • P Patel et al.

    Helicobacter pylori infection in childhood: risk factors and effect on growth

    Br Med J

    (1994)
  • G Bode et al.

    The coccoid forms of Helicobacter pylori. Criteria for their viability

    Epidemiol Infect

    (1993)
  • L Cellini et al.

    Coccoid Helicobacter pylori not culturable in vitro reverts in mice

    Microbiol Immunof.

    (1994)
  • K Hulten et al.

    Detection of Helicobacter pylori in Peruvian water sources by two PCR assays based on independent genes

    Gut.

    (1995)
  • RH Hunt

    Helicobacter pylori and spontaneous hypochlorhydria

  • H Jablonski et al.

    Helicobacter pylori (H.p) from patients with gastritis inhibit acid production more frequently than H.p from duodenal ulcer patients

    Gastroenterology.

    (1993)
  • J Defize et al.

    Inhibition of acid production by Campylobacter pylori in isolated guinea pig parietal cells

    Gastroenterology.

    (1989)
  • JS Hoffman et al.

    Rabbit and ferret parietal cell inhibition by Heticobacter species

    Dig Dis Sa.

    (1995)
  • SL Wilhoite et al.

    Increased prevalence of Helicobacter pylon antibodies in nurses

    Arch Intern Med.

    (1993)
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