Cell Reports Medicine
Volume 2, Issue 1, 19 January 2021, 100188
ArticleTargeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
Under a Creative Commons license
open access
Graphical Abstract
Keywords
chordoma
phase separation
transcription
transcription factor
transcriptional inhibition
targeted degradation
brachyury
super-enhancer
cyclin-dependent kinase
transcriptional condensate
Cited by (0)
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Present address: Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London SM2 5NG, UK
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Present address: Shared Resources, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
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Present address: Kronos Bio, Cambridge, MA 02139, USA
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Lead contact
© 2020 The Authors.