Prospects for preventing infant invasive GBS disease through maternal vaccination
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Preventing invasive GBS disease through maternal vaccination
The earliest evidence suggestive that maternal GBS vaccination might prevent invasive GBS disease in their infants was premised on studies by Carol Baker in the 1970s, which showed higher maternal serotype-specific capsular antibody levels being associated with lower risk for developing invasive GBS disease in neonates born to mothers colonized with the homotypic serotypes[21]. Further studies by others including more recently from Africa, corroborated these findings, although the differences
Competing interests
None.
Financial disclosure/support
SAM is funded in part by National Research Foundation/Department of Science and Technology: South African Research Chair Initiative Program and Medical Research Council of South Africa. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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