Cell Stem Cell
Volume 18, Issue 1, 7 January 2016, Pages 16-19
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Improving Stem Cell Therapeutics with Mechanobiology

https://doi.org/10.1016/j.stem.2015.12.007Get rights and content
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In recent years, it has become clear that mechanical cues play an integral role in maintaining stem cell functions. Here we discuss how integrating physical approaches and engineering principles in stem cell biology, including culture systems, preclinical models, and functional assessment, may improve clinical application in regenerative medicine.

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Present address: Department of Pharmacology and Department of Bioengineering, University of Illinois College of Medicine, Chicago, IL 60612, USA