Elsevier

Sleep Medicine

Volume 9, Issue 5, July 2008, Pages 473-474
Sleep Medicine

Editorial
Autonomic dysfunction in RBD – What can it teach us about disease progression?

https://doi.org/10.1016/j.sleep.2007.10.002Get rights and content

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    This probably reflects underlying synucleinopathy, since autonomic dysfunction has been identified in PD, DLB and MSA. The cardiac autonomic dysfunction of iRBD is similar in nature to that found in established synucleinopathy [16,18,20,40,44–48]. Autonomic dysfunction was strongly linked to the presence of RBD in PD [16], suggesting again, that RBD may indicate a specific disease subtype.

  • Sleep dysfunction and role of dysautonomia in Parkinson's disease

    2009, Parkinsonism and Related Disorders
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    The extent of decline was similar to that seen in PD patients [6]. Autonomic dysfunction was universally found in RBD, and it has been proposed that it is an important part of RBD pathology, i.e., some autonomic dysfunction is required to express the clinical phenotype of RBD [6]. Sleep apnoea can result in sleep disordered breathing.

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Disclosure: Dr. Postuma received personal compensation from Novartis for consulting services. Dr. Postuma was supported by the Fonds de la recherche en santé du Québec (FRSQ). Dr. Montplaisir received personal compensation as consultant (Boehringer Ingelheim, Servier, Shire Biochem), speaker (Boehringer, Shire), and received financial support for research activities from Sanofi Synthelabo, GlaxoSmithKline, the FRSQ and the Canadian Institute for Health Research (CIHR). J.F. Gagnon was supported by the FRSQ and the CIHR.

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