Original articleAre Myopic Eyes Less Likely to Have Diabetic Retinopathy?
Section snippets
Study Population
The Singapore Malay Eye Study is a population-based, cross-sectional study of urban Malay adults 40 to 80 years of age residing in Singapore. Study design and population details have been described elsewhere.22, 23, 24, 25 In brief, Malay subjects were selected from a national database using an age-stratified random sampling process. Of those eligible, 3280 (78.7% participation rate) were examined between 2004 and 2006. Diabetes mellitus was identified from plasma glucose of 200 mg/dl (11.1
Results
A total of 629 subjects with diabetes were included in the analysis. The mean age±standard deviation was 61.4±9.3 years, 265 (42.1%) were male, and the mean AL and SE were 23.40±1.01 mm and 0.02±2.09 D, respectively. The SE ranged from 16 to –25.5 D. Table 1 summarizes the demographic and systemic characteristics of study participants. Significant trends were noted for age, education, and smoking across refractive error groups. Myopic subjects tended to be younger (P<0.001), tended to have
Discussion
This article reports on the relationship between refractive errors and axial dimensions with DR over the range of hyperopia to high myopia in a population-based study in Singapore. Eyes that were more myopic and with longer AL and deeper ACD were less likely to have any DR, particularly vision-threatening DR, with no evidence seen for a threshold. The study suggests a continuous protective effect of myopia over the range of mild to high myopia on the risk of DR.
Many studies14, 15, 16, 20, 21
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Cited by (0)
Manuscript no. 2009-668.
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Supported by the National Medical Research Council (grant no.: 0796/2003; and Biomedical Research Council grant no.: 501/1/25-5).