Neuron
Volume 61, Issue 2, 29 January 2009, Pages 156-157
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Glia, Adenosine, and Sleep

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Sleep is regulated by a homeostatic process that has long been thought to involve adenosine (AD) originating from neurons. In this issue of Neuron, Halassa et al. present evidence that sleep homeostasis depends upon gliotransmission and associated accumulation of AD that dampens neuronal excitability.

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