Task-specific impairment of motor cortical excitation and inhibition in patients with writer's cramp
Section snippets
Acknowledgments
This research was supported by grants from the COFIN 2003. We thank Dr Patrizio Pasqualetti and Dr Michela Romani for statistical support.
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Cited by (30)
Effects of cerebellar theta-burst stimulation on arm and neck movement kinematics in patients with focal dystonia
2016, Clinical NeurophysiologyDecreased high-frequency center-of-pressure complexity in recently concussed asymptomatic athletes
2016, Gait and PostureCitation Excerpt :Increased intra-cortical inhibition in the motor cortex [45] and longer cortical silent periods following transcranial magnetic stimulation [46] are indicative of alterations to the corticospinal excitability and/or inhibitory capacity post-concussion [47]. This increased cortical inhibition has been associated with decreased muscle stiffness [48–50] and inhibition of prepared actions [51], which would be consistent with the present results. Though previous authors suggested that decreased COP complexity post-concussion may be due to increased co-contraction or stiffened musculature as an adaptation to decreased balance control [8,52], we found an increase in complexity when non-athlete participants were instructed to co-contract their lower extremity muscles.
Transcranial magnetic stimulation in dystonia
2013, Handbook of Clinical NeurologyCitation Excerpt :The SP is shortened in focal dystonia (Chen and Hallett, 1998; Espay et al., 2006; Kimberley et al., 2009), although this was not seen in all investigations (Stinear and Byblow, 2005). This abnormality is in general restricted to the symptomatic hand and is task specific, as the abnormality of the SP was seen in a pincer grasp task but not in a power grip task in patients with writer's cramp (Tinazzi et al., 2005). Intracortical inhibition can also be assessed with paired suprathreshold TMS pulses at longer intervals from 50 to 200 ms (Valls-Sole et al., 1992).
Neurophysiology of dystonia: The role of inhibition
2011, Neurobiology of DiseaseCitation Excerpt :This abnormality may be restricted to the symptomatic hand (Chen et al., 1997). Another observation is that the abnormality of the SP was seen in a pincer grasp task, but not a power grip task in patients with writer's cramp (Tinazzi et al., 2005). This might indicate some task specificity for the abnormality.