Polymer coating on a micropillar chip for robust attachment of PuraMatrix peptide hydrogel for 3D hepatic cell culture
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Alexander David Roth is a chemical engineering doctoral student in the Department of Chemical and Biomedical Engineering at Cleveland State University. His research is on simulating drug-induced liver injury using hepatic cell microarrays and developing miniature 3D tissue constructs for studying liver cancer. He received in undergraduate degree in biological engineering from Cornell University in 2009 and his master's degree in chemical engineering from The Ohio State University in 2013.
Pratap Lama is an undergraduate student in Cleveland State University majoring in chemical engineering. He holds the associates degree in science from Lakeland community college. He is a former treasurer of the Cleveland State University Chapter of Tau Beta Pi and an active member in American Institute of Chemical Engineers (AIChE). He worked under the direction of Dr. Moo Yeal Lee, focusing on micropillar chip surface chemistry and Puramatrix peptide hydrogel. Pratap started working Parker Hannifin Corporation for an engineering coop in May 2015, where he is currently working part time as an engineering support.
Stephen Dunn received his undergraduate degree in chemical engineering from Cleveland State University in 2016. Stephen wrote his honor's thesis on “Simulating Drug-Induced Liver Injury (DILI) Using Hepatic Cell Microarrays” under the supervision of Dr. Moo-Yeal Lee. While at Cleveland State, Stephen was a member of Tau Beta Pi and the American Institute of Chemical Engineers (AIChE). Presently, Stephen works as a graduate engineer for HWH Architects Engineers Planners Inc.
Stephen Hong earned his Bachelor's Degree in Biological and Environmental Engineering from Cornell University and his Master's Degree in Education from the University of Nevada, Las Vegas. He currently works as a laboratory technician with Dr. Moo-Yeal Lee at Cleveland State University. Stephen has research interests in 3D tissue model and cell migration utilizing high-throughput microarray chip technology for drug development.
Dr. Moo-Yeal Lee received his Ph.D. degree in chemical and biomolecular engineering from KAIST, South Korea in 1999. At Cleveland State University, Solidus Biosciences Inc., and RPI, Dr. Lee focused on developing automatable, high-throughput microarray chip platforms and instruments that are used for miniaturized biochemical- and cell-based assays to assess metabolism and toxicology. Dr. Lee worked on underlying technology for protein and cell encapsulation in hydrogels and “bioprinting” on glass and plastic chip platforms for high-throughput, high-content assays. Current areas of research include biological printing with liquid-dispensing robots for miniaturized three-dimensional cell culture and organotypic tissue constructs via layer-by-layer printing.