Elsevier

Microbes and Infection

Volume 9, Issue 10, August 2007, Pages 1156-1166
Microbes and Infection

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Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes

https://doi.org/10.1016/j.micinf.2007.05.003Get rights and content
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Abstract

The Listeria monocytogenes genome includes a large family of proteins harbouring leucine-rich repeats known as internalins (Inl). The generation of novel mutants and comparative analysis of Inl variability among Listeria and other bacterial genomes suggest that beyond the extensively-studied invasins, InlA and InlB, additional internalins also play important functions in the infectious process.

Keywords

Leucine-rich repeat
Pathogenicity
Surface proteins
Virulence factors
Invasins

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