Clinical studyDoppler Vibrometry: Assessment of Arterial Stenosis by Using Perivascular Tissue Vibrations without Lumen Visualization
Section snippets
Study Population
In this prospective feasibility study, 16 patients (eight women) who were scheduled to undergo abdominal or pelvic angiography at the University of Washington interventional radiology laboratory were recruited for examination before angiography. Angiography was indicated in these patients to evaluate suspected stenoses on the basis of a previous conventional duplex US examination. The symptoms that prompted the initial duplex examination were varied and related to different vascular beds (eg,
Results
A total of 18 arteries were imaged in the 16 patients. Of the 18 arteries, stenoses (diameter reduction, 43%–91%) were angiographically measured in six renal arteries, four hepatic arteries, three iliac arteries, and one superior mesenteric artery yielding vibrometry data. One patient with a 79% diameter reduction hepatic artery stenosis did not yield measurable vibrometry data due to significant bowel gas precluding adequate US data acquisition. Three iliac arteries were normal (<30% diameter
Discussion
Lees and colleagues (4, 10, 11) developed the phonoangiography method for predicting the minimum lumen diameter of a carotid stenosis on the basis of a quantitative analysis of the frequency spectrum of cervical bruits detected on the skin surface. The hypothesis behind quantitative phonoangiography is that the frequency spectrum of the sound produced by vessel wall vibrations is dependent on the effective diameter of the turbulent jet, assuming that the systolic flow rate to the brain is the
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None of the authors have identified a conflict of interest.
From the 2008 SIR annual meeting.