Craniomaxillofacial traumaDoes Early Repair of Orbital Fractures Result in Superior Patient Outcomes? A Systematic Review and Meta-Analysis
Section snippets
Study Design and Sample
To address the research question, we developed a protocol for a systematic literature review.13 We integrated evidence from primary studies and published systematic reviews.14, 15, 16 The study population was composed of all articles published until October 2018. For inclusion in the study sample, we defined the target population as children or adults with orbital fractures due to facial trauma, in addition to articles that defined interventions as having a shorter or longer timing (as defined
Results
Overall, 1,160 articles were reviewed, of which 20 met the inclusion criteria (Fig 1). These studies included a total of 614 patients undergoing operative orbital floor reconstruction, of whom 22 were enrolled in an RCT. These studies included 1 narrative review, 2 systematic reviews, 1 RCT, and 16 nonrandomized cohort studies7,30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51 comparing interventions, thus providing a post hoc analysis of the association
Discussion
The purpose of this study was to determine whether the available evidence pertaining to the timing of operative management in patients with orbital fractures portrayed differences in clinical outcomes and complication rates. We hypothesized that a shorter time to surgery would be associated with more favorable prognoses. Moreover, we aimed to compare patient outcomes, including preoperative and postoperative complications, between a shorter interval to intervention and a longer interval to
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Conflict of Interest Disclosures: Dr Dorafshar receives royalties from Elsevier and KLS Martin and indirect research support from De Puy Synthes. All other authors do not have any relevant financial relationship(s) with a commercial interest.