Dentoalveolar surgeryComparison of Clinical Efficacies of Preoperatively Initiated Naproxen Sodium–Codeine Phosphate in Combination, Diclofenac Potassium, and Benzydamine Hydrochloride for Pain, Edema, and Trismus After Extraction of Impacted Lower Third Molar: A Randomized Double-Blind Study
Section snippets
Materials and Methods
This randomized double-blind study was conducted in patients who presented to the Department of Oral and Maxillofacial Surgery, Yüzüncü Yıl University, with the indication of impacted lower third molar extraction. For all study groups, the following were accepted as inclusion criteria: absence of any systemic disease (Class I individuals according to the American Society of Anesthesiologists), no history of allergy, nonpregnant patients, and no medication intake for the week leading up to
Results
The study included a total of 90 patients, of whom 46 were women and 44 men. The mean age of the patients was 24.03 ± 4.82 years, and ages ranged between 18 and 39 years. The mean operation time was 22.3 ± 2.72 minutes and was similar between groups.
For the naproxen sodium–codeine phosphate group, pain was most intense at hour 3, whereas pain for the diclofenac potassium and benzydamine HCL groups was most intense at hour 6. According to the comparison of VAS scores between groups (excluding
Discussion
The occurrence of pain, edema, and trismus after the extraction of an impacted tooth often creates a situation in which patients retreat from social life. A range of other complications, including lost productivity and psychological distress, constitute a sufficient reason for us to call these extractions into question. Hence, it is important to recognize that ongoing studies have sought to examine the viable strategies for the successful management of these complications.21 Our aim in this
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Pharmacological and Non-Pharmacological Methods of Postoperative Pain Control Following Oral and Maxillofacial Surgery: A Scoping Review
2021, Journal of Oral and Maxillofacial SurgeryEvaluation of the effects of concentrated growth factors or advanced platelet rich-fibrin on postoperative pain, edema, and trismus following lower third molar removal: A randomized controlled clinical trial
2020, Journal of Stomatology, Oral and Maxillofacial SurgeryPreemptive use of oral nonsteroidal anti-inflammatory drugs for the relief of inflammatory events after surgical removal of lower third molars: A systematic review with meta-analysis of placebo-controlled randomized clinical trials
2020, Journal of Cranio-Maxillofacial SurgeryCitation Excerpt :For trismus management, statistically significant results were obtained in studies that used meloxicam 7.5 mg (Avelar et al., 2012), meloxicam 15 mg (Solis et al., 2016), and ibuprofen 400 mg and etoricoxib 120 mg (Albuquerque et al., 2017). However, Costa et al. (2015) (etoricoxib 120 mg), Kaplan and Eroglu (2016) (flurbiprofen 200 mg, sodium diclofenac 100 mg, and tenoxicam 20 mg), and Cigerim and Eroglu (2018) (potassium diclofenac 50 mg) did not obtain statistically significant results in relation to postoperative reduction of edema and trismus. Moreover, Akbulut et al. (2014) did not observe significant improvement of trismus after preemptive administration of potassium diclofenac 50 mg, naproxen-sodium, or etodolac (200 mg), while Orozco-Solis et al. (2016) did not observe statistically significant differences regarding edema when associated with the preemptive use of diclofenac (100 mg) or meloxicam (15 mg).
Selection of Submucosal Steroids to Minimize Postsurgical Pain
2018, Journal of Oral and Maxillofacial SurgeryAnalgesic efficacy of naproxen-codeine, naproxen+dexamethasone, and naproxen on myofascial pain: A randomized double-blind controlled trial
2023, Cranio - Journal of Craniomandibular and Sleep Practice
Conflict of Interest Disclosures: None of the authors have any relevant financial relationship(s) with a commercial interest.