Basic ResearchAntibacterial Activity of Endodontic Sealers by Modified Direct Contact Test Against Enterococcus faecalis
Section snippets
Sealers
Seven endodontic sealers were used in this study: an epoxy resin–based sealer, AH Plus (Dentsply International Inc, York, PA); 2 polymethacrylate resin–based sealers, Epiphany SE (Pentron Clinical Technologies LLC, Wallingford, CT) and EndoRez (Ultradent, South Jordan, UT); 2 calcium hydroxide–based sealers, Apexit Plus (Vivadent, Schaan, Liechtenstein) and Sealapex (SybronEndo Corporation, Orange, CA); a calcium hydroxide–calcium silicate complex sealer, iRoot SP; and a zinc
Results
The results of the antibacterial effects of the endodontic sealers from modified DCT are presented in Fig. 1. Fresh sealers and sealers set for 1, 3, and 7 days showed differences in their activity against E. faecalis. The antibacterial effect of the sealers was relatively stable for up to 3 days. However, after 7 days most sealers had lost much of their antibacterial effect except for Sealapex and EndoRez.
Fresh iRoot SP eradicated all bacteria within 2 minutes of contact. Fresh AH Plus and
Discussion
An ideal endodontic sealer should be biocompatible and dimensionally stable; it should seal well and have a strong, long-lasting antimicrobial effect 15, 16, 17. Antibacterial activity of sealers might help to eliminate residual microorganisms that have survived the chemomechanical instrumentation and thereby improve the success rate of endodontic treatment. One of the challenges in endodontic research has been the lack of standardized in vitro and in vivo protocols for the testing of the
References (35)
- et al.
Antibacterial properties of four endodontic sealers
J Endod
(2008) - et al.
Antimicrobial activity and flow rate of newer and established root canal sealers
J Endod
(2000) - et al.
The antimicrobial effect within dentinal tubules of four root canal sealers
J Endod
(1996) - et al.
In vitro antibacterial activities of root-canal sealers by using two different methods
J Endod
(2004) - et al.
Antibacterial effect of selected root-end filling materials
J Endod
(2006) - et al.
Enterococcus faecalis: its role in root canal treatment failure and current concepts in retreatment
J Endod
(2006) Antimicrobial effect of root canal cements
J Endod
(1980)- et al.
In vitro antibacterialactivity of endodontic sealers
J Dent
(2006) - et al.
Release of formaldehyde by 4 endodontic sealers
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
(1999) - et al.
The properties of endodontic sealer cements
J Endod
(1988)
Release of calcium and hydroxyl ions from set endodontic sealers containing calcium hydroxide
J Endod
Evaluation of pH and calcium ion release of Acroseal sealer in comparison with Apexit and Sealapex sealers
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
Evaluation of pH and calcium ion release of three root canal sealers
J Endod
Dentin enhances the antibacterial effect of mineral trioxide aggregate and bioaggregate
J Endod
The calcium silicate hydrates
Cement and Concrete Research
Influence of apatite seeds on the synthesis of calcium phosphate cement
Biomaterials
Water sorption and solubility of methacrylate resin-based root canal sealers
J Endod
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