Journal of Molecular Biology
Volume 428, Issue 20, 9 October 2016, Pages 4115-4128
Contribution of Bistability and Noise to Cell Fate Transitions Determined by Feedback Opening
Under a Creative Commons license
open access
Graphical Abstract
Abbreviations
TF
transcription factor
dox
doxycycline
ORF
open reading frame
smFISH
single molecule fluorescence in situ hybridization
S
logarithmic sensitivity
fOLM
open-loop function
fEQ
equivalence function
Smax(ω)
maximal sensitivity of the fOLM
rtTA
reverse tetracycline transactivator
GEV
Gal4-estrogen receptor-Vp16
GFP
green fluorescent protein
I.C.
initial condition
Keywords
positive feedback loop
stochastic gene expression
synthetic biology
Cited by (0)
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C.H. and V.J. contributed equally to this work.
© 2016 The Authors. Published by Elsevier Ltd.