Original ArticleMultivariate meta-analysis of individual participant data helped externally validate the performance and implementation of a prediction model
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Keywords
Risk prediction
Prognostic model
Individual participant data (IPD)
Multivariate meta-analysis
External validation
Calibration
Discrimination
Heterogeneity
Model comparison
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Funding: R.D.R. and J.E. are supported by funding from a multivariate meta-analysis grant from the MRC Methodology Research Programme (grant reference number: MR/J013595/1). K.I.E.S. was supported by funding from the MRC Midlands Hub for Trials Methodology Research, at the University of Birmingham (Medical Research Council Grant ID G0800808). K.G.M.M. acknowledges financial contribution by the Netherlands Organisation for Scientific Research (project 9120.8004 and 918.10.615).
Crown copyright © 2016 Published by Elsevier Inc.