Journal of American Association for Pediatric Ophthalmology and Strabismus
Major ArticleMyopia and anterior segment optical coherence tomography findings in laser-treated retinopathy of prematurity eyes
Section snippets
Subjects and Methods
This study was approved by the University of California Los Angeles Institutional Review Board, followed the tenets of the Declaration of Helsinki, and was compliant with the US Health Insurance Portability and Accountability Act of 1996. Subjects were recruited at the Stein Eye Institute, University of California Los Angeles. Informed consent was obtained from the legal guardian prior to recruitment.
Three groups of children (<18 years of age) were recruited: (1) a control group of children
Results
A total of 50 eyes of 50 patients were included: 19 eyes of full-term control subjects, 19 eyes from preterm infants who were monitored only, and 12 eyes of preterm infants with type 1 ROP that received laser treatment (Table 1). Of the preterm monitored eyes, 1 was unknown due to unavailable birth records, 7 had no ROP, and 4 had type 2 ROP; of those with type 2 ROP, all were zone 2 without plus disease that eventually regressed—3 had stage 2 and 1 had stage 1 (Table 1). There were no
Discussion
Vision loss in preterm children can be multifactorial, due to macular dragging, refractive error, strabismus, amblyopia, optic atrophy, or developmental delay. High myopia early in life is common in preterm children and may be affected by either prematurity itself or ROP treatments.17 Cryotherapy and laser have been associated with nonaxial myopia as opposed to axial myopia seen in non-preterm children.18 Studies have also implicated increased corneal curvature, decreased ACD, abnormal
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Cited by (0)
This research was supported by an unrestricted grant from Research to Prevent Blindness (SLP).
Disclosures: Dr. Sarraf is a consultant for Amgen, Bayer, Genentech, Optovue; Research: Amgen, Genentech, Heidelberg, Topcon, Optovue, Regeneron; and Speaker: Novartis, Optovue. The other authors have no disclosures.