Immunity
Volume 43, Issue 1, 21 July 2015, Pages 9-11
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Passenger Mutations Identified in the Blink of an Eye

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Passenger mutations specific to particular mouse strains can distort experimental outcomes. In this issue of Immunity, Vanden Berghe et al. (2015) demonstrate that passenger mutations are frequent in most genetically engineered congenic mice and persist even after extensive backcrossing.

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