Primary breast angiosarcoma in a young woman

Highlights

• Angiosarcomas are rare malignant vascular tumors of the breast.

• They frequently are associated with previous breast radiotherapy.

• Total mastectomy without axillary lymphadenectomy appears to be the only treatment.

• Chemotherapy and radiotherapy have not proven any benefit in terms of survival.

Abstract

Introduction

Angiosarcomas of the breast are a rare subtype of sarcomas that frequently are diagnosed after radiation therapy for primary breast cancer. Primary angiosarcomas are rare entities accounting 0.05% of all malignant breast neoplasm.

Presentation of Case

We report a case of primary angiosarcoma of the breast in a 25 years woman, with no previous radiotherapy, treated with a total mastectomy followed by radio-chemotherapy.

Discussion

Total mastectomy appears to be the only treatment known that has proven to benefit these patients. Adjuvant treatment has not proven value up until today. The 5-year disease free survival for grade 1 tumors can be as high as 76%, and up to 15% for grade 3.

Conclusion

Due to the rarity of these tumors there is no standard therapies approach.