Elsevier

International Journal of Cardiology

Volume 340, 1 October 2021, Pages 119-121
International Journal of Cardiology

Short communication
Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients

https://doi.org/10.1016/j.ijcard.2021.08.018Get rights and content

Highlights

  • Fulminant myocarditis may occur following SARS-CoV2 mRNA vaccination requiring mechanical cardiac support.

  • It is important to recognize features of systemic hyperinflammatory syndrome following SARS-CoV2 mRNA vaccination.

Abstract

Immune-mediated myocardial injury following Severe Acute Respiratory Syndrome Coronavirys-2 (SARS-CoV2) infection has been described in adults and children. Cases of myocarditis following immunization for SARS-CoV2 have recently been documented, mostly associated with mild severity and spontaneous recovery. We herein report two cases of fulminant myocarditis following BNT162b2 mRNA Covid-19 vaccination associated with systemic hyperinflammatory syndrome and refractory shock requiring support with veno-arterial extracorporeal membrane oxygenation.

Keywords

Vaccine
Myocarditis
Coronavirus
Covid-19

Cited by (0)

1

The first two authors equally contributed to the realization of this manuscript

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