Tuesday abstractTu1139 FEASIBILITY AND SAFETY OF ENDOSCOPIC SUBMUCOSAL DISSECTION FOR SUPERFICIAL ESOPHAGEAL NEOPLASMS IN ELDERLY PATIENTS: A SINGLE CENTER, LARGE SCALE, RETROSPECTIVE STUDY
Introduction
Although the number of elderly patients with superficial esophageal neoplasms (SENs) has been steadily increasing, there is still an evident lack of studies focused on the clinical outcome of esophageal endoscopic submucosal dissection (ESD) in the elderly. We investigated the feasibility and safety of ESD for SENs in elderly patients.
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Patients and Methods
Patients who underwent ESD for SENs between December 2005 to December 2017 were eligible. Clinical features and treatment outcomes according to the three age groups (not-old, < 65 years; young-old, 65-74 years; middle and oldest-old, > 74 years) were retrospectively reviewed using medical records.
Results
ESD was performed in 426 patients with 475 lesions, including 97 cases (20.4%) of dysplasia, 364 cases (76.6%) of squamous cell carcinoma and 14 cases (3%) of adenocarcinoma. The age was divided into three groups, the not-old (n=200), young-old (n=179) and middle & oldest-old (n=47). Gender, Smoking and characteristics of tumor (circumference, location, lesion size, resected specimen size, histology and depth of invasion) did not differ. Underlying disease such as hypertension (not-old vs.
Conclusion
ESD is a feasible and effective procedure for the treatment of SENs in elderly patients as in non-elderly patients which showed favorable outcomes.