Original ArticleClinical EndoscopyColorectal neoplasia in Asia: a multicenter colonoscopy survey in symptomatic patients
Section snippets
Study population
This study was conducted between July 2004 and April 2005 in 17 endoscopy centers in 10 Asian countries (Appendix 1, available online at www.giejournal.org). All participating centers were secondary or tertiary referral endoscopy centers. We included consecutive symptomatic patients who were referred to these endoscopy centers for colonoscopy. Hence, patients included in this study were representative of the typical patients who were managed in the study centers. Patients who had previous
Patients
A total of 7290 patients had undergone colonoscopy in the study endoscopy centers during the study period. Fifty-four patients who were younger than 16 years old and 533 patients who had previous colonic examination were excluded (Fig. 1). The results of the 1204 asymptomatic individuals who underwent colonoscopy for screening purposes were not included in this study. Thirty-five white patients were also excluded in the analysis of this Asian study. The mean age (SD) of the 5464 symptomatic
Discussion
Colorectal cancer is increasing in Asian countries1, 2; however, there is a paucity of data from this region. Although the incidence of colorectal cancer may be derived from different cancer registries, including the GOLBOCAN,1 data on the precursor lesion, colorectal adenoma, are lacking. This multinational, multicenter, and multiracial study provided a glimpse on the epidemiology of colorectal neoplasm in Asia. This is the first prospective study to examine the epidemiology of colorectal
Acknowledgments
We would like to thank all members of the Asia Pacific Working Group on Colorectal Cancer, Professor William Chao, Professor Graeme Young, Miss Bing-yee Suen, and the staff of all participating endoscopy centers for their contribution to this study.
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