Keynote PaperThe poetry of mycological accomplishment and challenge☆
Section snippets
Pathogenesis
Keeping Burn’s thoughts in mind, I’ll begin with a story of adaptation in pathogenesis. We’ll start with flax rust, the disease of Linum species caused by the rust, Melampsora lini (Fig. 2), and follow it to North Dakota. The gene-for-gene hypothesis to explain host resistance and pathogen avirulence was developed in that state by Flor in mid-twentieth century. It was the first study of the genetics of both host and parasite and represents one of the great accomplishments of mycology (Flor, 1971
Cell biology
Cell biology is the next topic and the strides made from the combination of computer-enhanced light microscopy, fluorescently tagged molecules and mutation by molecular genetics represent accomplishments that may be unparalleled in recent mycological research. To choose a poem for cell biology, I am going south to England for a poem oft found in American middle-school anthologies, Percy Bysse Shelly’s Ozymandias. Shelly and his poet friend, Horace Smith, competed to write a sonnet about the
Genomics, evolution and ecology
Mention of genomes of Dimargaris or Neolecta provides an introduction to the final segment of my presentation. I am going to combine genomics with the two topics that interest the most IMC9 delegates, evolution and ecology, because I believe that genomics will have its greatest impact on these areas. On the one hand genomics is merely the latest in a series of technological advances, beginning with enzyme electrophoresis, that have revealed more and more about genetics. On the other it seems to
Acknowledgements
Support is acknowledged from NIAID 1R01AI070891, NIGMS R01 RGM081597, and NSF DEB 0516511. Thanks are due Tom Friesen, Greg Jedd and Tom Wolpert for discussions about pathology and cell biology.
References (48)
- et al.
Dating the molecular clock in fungi – how close are we?
Fungal Biology Reviews
(2010) - et al.
Host–microbe interactions: shaping the evolution of the plant immune response
Cell
(2006) - et al.
The hypersensitive response facilitates plant infection by the necrotrophic pathogen Botrytis cinerea
Current Biology
(2000) Fungal evo-devo: organelles and cellular complexity
Trends in Cell Biology
(2011)The origin at 150: is a new evolutionary synthesis in sight?
Trends in Genetics
(2009)- et al.
The fungi
Current Biology
(2009) - et al.
Plants versus pathogens: an evolutionary arms race
Functional Plant Biology
(2010) - et al.
Ultrastructure and development of septa in hyphae of Rhizoctonia solani
Mycologia
(1963) Researches on Fungi
(1933)- et al.
A multilocus genealogical approach to phylogenetic species recognition in the model eukaryote Neurospora
Evolution
(2003)
Reproductive isolation and phylogenetic divergence in Neurospora: comparing methods of species recognition in a model eukaryote
Evolution
A map of human genome variation from population-scale sequencing
Nature
Flax rust resistance gene specificity is based on direct resistance-avirulence protein interactions
Annual Review of Phytopathology
Population genomics and local adaptation in wild isolates of a model microbial eukaryote
Current status of the gene-for-gene concept
Annual Review of Phytopathology
Host-specific toxins: effectors of necrotrophic pathogenicity
Cellular Microbiology
The Stagonospora nodorum-wheat pathosystem involves multiple proteinaceous host-selective toxins and corresponding host sensitivity genes that interact in an inverse gene-for-gene manner
Plant Journal
Emergence of a new disease as a result of interspecific virulence gene transfer
Nature Genetics
Cellodextrin transport in yeast for improved biofuel production
Science
Coccidioidomycosis: changing perceptions and creating opportunities for its control
Uber die Substruktur von Polystictus versicolor L.
Archiv Fur Mikrobiologie
A new self-assembled peroxisomal vesicle required for efficient resealing of the plasma membrane
Nature Cell Biology
The plant immune system
Nature
Darwinian evolution in the light of genomics
Nucleic Acids Research
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2013, Microbial Biotechnology
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The opportunity to open an International Mycological Congress is a singular honor and I offer my sincere thanks to Nick Read, Chair of the IMC9 program committee, and its membership: Simon Avery, Nicholas Clipson, Geoff Gadd, Neil Gow and Geoff Robson. Thanks also are due to Neil Gow for his thoughtful introduction and Nina Cosgrove and her crew from Elsevier for implementing the committee’s vision for this glorious congress.