EGM clinical caseExtreme alkaline phosphatase elevation in an asymptomatic geriatric patient
Introduction
Prostate cancer is a disease of men over the age of 50 years, and the trend towards an aging worldwide population is likely to lead to an increased incidence of prostate cancer. Bone metastases of prostate cancer are commonly accompanied by elevation of alkaline phosphatase (ALP) [2].
In this case report, we present an elderly patient who referred to us with extremely isolated ALP elevation without any complaints, was diagnosed metastatic prostate cancer.
Section snippets
Case report
A 78-year-old male admitted to our geriatrics outpatient clinic with isolated ALP elevation. He had hypertension for 10 years and he has been using ACE inhibitor/hydrochlorothiazide combination. There were no complaints like dyspepsia, jaundice, bone pain, obstructive and irritating voiding symptoms, trauma and symptoms suggestive of impaired renal function. He had only mild weakness. His medical history was unremarkable. Physical examination on admission was normal. Hepatobiliary system was
Discussion
Alkaline phosphatases are a group of enzymes found primarily in the liver (isoenzyme ALP-1) and bone (isoenzyme ALP-2). The primary importance of measuring alkaline phosphatase is to check the possibility of bone disease or liver disease. Pathologic evaluation of ALP may be due to hepatobiliary diseases, bone diseases, and malignancies [9].
Hepatobiliary ultrasoundgraphy and other liver function tests of our patient were normal. We wanted to see his X-ray graphies of bones for considering a kind
Disclosure of interest
The authors declare that they have no conflicts of interest concerning this article.
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