Developmental Cell
Volume 49, Issue 2, 22 April 2019, Pages 157-158
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A PBX/MEIS Complex Balances Reproduction and Somatic Resilience

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Resource reallocation to metabolic processes promoting reproduction is critical for the survival of a species and therefore is tightly regulated. In this issue of Developmental Cell, Dowen (2019) finds that a PBX/MEIS homeodomain transcription factor complex controls a transcriptional network that balances reproduction versus longevity and somatic maintenance.

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